Ribosomes are essential to cellular life and the genes for their RNA components are the
most conserved and transcribed genes in bacteria and archaea. Ribosomal RNA genes are …

Ribosomal proteins (RPs) are highly conserved across the bacterial and archaeal domains.
Although many RPs are essential for survival, genome analysis demonstrates the absence …

Ribosomal RNA (rRNA) genes, essential to all forms of life, have been viewed as highly
conserved and evolutionarily stable, partly because very little is known about their natural …

Background The concept of ribosomal constraints on rRNA genes is deduced primarily
based on the comparison of consensus rRNA sequences between closely related species …

We examined intragenomic variation of paralogous 5S rRNA genes to evaluate the concept
of ribosomal constraints. In a dataset containing 1161 genomes from 779 unique species, 96 …

Abstract Background Structured noncoding RNAs perform many functions that are essential
for protein synthesis, RNA processing, and gene regulation. Structured RNAs can be …

Multiple copies of a given ribosomal RNA gene family undergo concerted evolution such
that sequences of all gene copies are virtually identical within a species although they …

Microbiologists utilize ribosomal RNA genes as molecular markers of taxonomy in surveys of
microbial communities. rRNA genes are often co-located as part of an rrn operon, and …

The level of sequence heterogeneity among rrn operons within genomes determines the
accuracy of diversity estimation by 16S rRNA-based methods. Furthermore, the occurrence …

Whole-transcriptome sequencing studies from recent years revealed an unexpected
complexity in transcriptomes of bacteria and archaea, including abundant non-coding RNAs …