Novel therapeutic strategies for renal graft preservation and their potential impact on the future of clinical transplantation
S Juriasingani, M Akbari, P Luke… - Current Opinion in Organ …, 2019 - journals.lww.com
Progress has been made in investigating improvements and alternatives to cold
preservation. Promising therapeutic strategies have also been studied in the context of cold …
preservation. Promising therapeutic strategies have also been studied in the context of cold …
I: negative effect of cold ischemia on initial renal function
BM Stubenitsky, MH Booster, L Brasile, EM Green… - ASAIO …, 2000 - journals.lww.com
Correlation between post-transplant function and exposure to cold ischemia (CI) during
preservation has been reported. We attempted to identify the effect of CI on renal function …
preservation has been reported. We attempted to identify the effect of CI on renal function …
Minimising cold ischaemic injury in an experimental model of kidney transplantation
SA Hosgood, A Bagul… - European journal of …, 2011 - Wiley Online Library
Eur J Clin Invest 2011; 41 (3): 233–240 Abstract Background Cold ischaemic (CI) injury is
associated with reduced renal graft function and survival. However, there is little evidence …
associated with reduced renal graft function and survival. However, there is little evidence …
[HTML][HTML] Preservation solutions for static cold storage of kidney allografts: a systematic review and meta-analysis
JM O'Callaghan, SR Knight, RD Morgan… - American Journal of …, 2012 - Elsevier
Static cold storage is the most prevalent method for renal allograft preservation. Several
solutions have been designed to counteract the detrimental effects of cold ischemia and …
solutions have been designed to counteract the detrimental effects of cold ischemia and …
Role of temperature in reconditioning and evaluation of cold preserved kidney and liver grafts
T Minor, C von Horn, A Paul - Current Opinion in Organ …, 2017 - journals.lww.com
Machine perfusion after conventional cold storage is beneficial for ulterior function after
transplantation. Cold grafts should be initially perfused at low temperatures allowing for …
transplantation. Cold grafts should be initially perfused at low temperatures allowing for …
[HTML][HTML] Current evidence and future perspectives to implement continuous and end-ischemic use of normothermic and oxygenated hypothermic machine perfusion in …
M Foguenne, S MacMillan, P Kron, J Nath… - Journal of clinical …, 2023 - mdpi.com
The use of high-risk renal grafts for transplantation requires the optimization of pretransplant
assessment and preservation reconditioning strategies to decrease the organ discard rate …
assessment and preservation reconditioning strategies to decrease the organ discard rate …
A pilot study assessing the feasibility of a short period of normothermic preservation in an experimental model of non heart beating donor kidneys
SA Hosgood, AD Barlow, PJ Yates, MGJ Snoeijs… - Journal of Surgical …, 2011 - Elsevier
BACKGROUND: Restoring metabolism to an organ after hypothermic storage and before
transplantation could reverse some of the detrimental effects of ischemic injury. This may be …
transplantation could reverse some of the detrimental effects of ischemic injury. This may be …
Therapeutic hypothermia in organ donors: follow-up and safety analysis
D Malinoski, MS Patel, DA Axelrod, K Broglio… - …, 2019 - journals.lww.com
Background. In a recent trial, targeted mild hypothermia in brain-dead organ donors
significantly reduced the incidence of delayed graft function after kidney transplantation. This …
significantly reduced the incidence of delayed graft function after kidney transplantation. This …
Consequences of cold ischemic injury of kidneys in clinical transplantation
AK Salahudeen - 2004 - journals.sagepub.com
Cold storage allows the effective utilization of organs retrieved for transplantation. However,
prolonged cold ischemia contributes to organ damage and increases patients' morbidity and …
prolonged cold ischemia contributes to organ damage and increases patients' morbidity and …
[HTML][HTML] Subnormothermic Oxygenated Machine Perfusion (24 h) in DCD Kidney Transplantation
Background. Ex vivo kidney perfusion is an evolving platform that demonstrates promise in
preserving and rehabilitating the kidney grafts. Despite this, there is little consensus on the …
preserving and rehabilitating the kidney grafts. Despite this, there is little consensus on the …