Human umbilical cord mesenchymal stem cell exosomes alleviate sepsis-associated acute kidney injury via regulating microRNA-146b expression

R Zhang, Y Zhu, Y Li, W Liu, L Yin, S Yin, C Ji, Y Hu… - Biotechnology …, 2020 - Springer
Human umbilical cord mesenchymal stem cell-derived exosomes (HucMSC-Ex) are a
promising tool for the repair of acute kidney injury (AKI) caused by cisplatin and …

[HTML][HTML] Exosomes released by human umbilical cord mesenchymal stem cells protect against renal interstitial fibrosis through ROS-mediated P38MAPK/ERK …

B Liu, D Hu, Y Zhou, Y Yu, L Shen, C Long… - American Journal of …, 2020 - ncbi.nlm.nih.gov
Mesenchymal stem cells (MSCs) and their conditioned medium attenuate renal fibrosis in an
irreversible model of unilateral ureteral obstruction (UUO). However, the key components …

[HTML][HTML] Exosomal miR-125b-5p deriving from mesenchymal stem cells promotes tubular repair by suppression of p53 in ischemic acute kidney injury

JY Cao, B Wang, TT Tang, Y Wen, ZL Li, ST Feng… - Theranostics, 2021 - ncbi.nlm.nih.gov
Mesenchymal stem cells-derived exosomes (MSC-exos) have attracted great interest as a
cell-free therapy for acute kidney injury (AKI). However, the in vivo biodistribution of MSC …

Mesenchymal stem cells-derived exosomes ameliorate ischemia/reperfusion induced acute kidney injury in a porcine model

J Huang, H Cao, B Cui, X Ma, L Gao, C Yu… - Frontiers in cell and …, 2022 - frontiersin.org
Exosomes are membrane-enclosed vesicles secreted by cells, containing a variety of
biologically active ingredients including proteins, nucleic acids and lipids. In this study, we …

Exosomes derived from mesenchymal stem cells ameliorate renal ischemic-reperfusion injury through inhibiting inflammation and cell apoptosis

L Li, R Wang, Y Jia, R Rong, M Xu, T Zhu - Frontiers in Medicine, 2019 - frontiersin.org
This study aimed to investigate the underlying mechanism of mesenchymal stem cells
(MSCs) on protection of renal ischemia reperfusion injury (IRI). Exosomes originated from …

Exosomes from human‐bone‐marrow‐derived mesenchymal stem cells protect against renal ischemia/reperfusion injury via transferring miR‐199a‐3p

G Zhu, L Pei, F Lin, H Yin, X Li, W He… - Journal of cellular …, 2019 - Wiley Online Library
Renal ischemia/reperfusion (I/R) injury is the main reason for acute kidney injury (AKI) and is
closely related to high morbidity and mortality. In this study, we found that exosomes from …

Exosomes derived from mesenchymal stem cells ameliorate hypoxia/reoxygenation‐injured ECs via transferring MicroRNA‐126

Q Pan, Y Wang, Q Lan, W Wu, Z Li… - Stem Cells …, 2019 - Wiley Online Library
Mesenchymal stem cells (MSCs) show protective effects on ischemia/reperfusion‐(I/R‐)
induced endothelial cell (EC) injury and vascular damage. Stem cell‐released exosomes …

Exosomes derived from human umbilical cord blood mesenchymal stem cells stimulate regenerative wound healing via transforming growth factor-β receptor …

Y Zhang, Y Pan, Y Liu, X Li, L Tang, M Duan… - Stem cell research & …, 2021 - Springer
Background Scar formation is a common consequence of skin wound healing, and no
effective treatment exists. Umbilical cord blood mesenchymal stem cells (UCB-MSCs) can …

Exosomes released by human umbilical cord mesenchymal stem cells protect against cisplatin-induced renal oxidative stress and apoptosis in vivo and in vitro

Y Zhou, H Xu, W Xu, B Wang, H Wu, Y Tao… - Stem cell research & …, 2013 - Springer
Introduction Administration of bone marrow mesenchymal stem cells (MSCs) or secreted
microvesicles improves recovery from acute kidney injury (AKI). However, the potential roles …

MiR‐20a‐containing exosomes from umbilical cord mesenchymal stem cells alleviates liver ischemia/reperfusion injury

L Zhang, Y Song, L Chen, D Li, H Feng… - Journal of cellular …, 2020 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been proved to exert considerable therapeutic effects
on ischemia‐reperfusion (I/R)‐induced injury, but the underlying mechanism remains …