Directing dendritic cell immunotherapy towards successful cancer treatment

RL Sabado, N Bhardwaj - Immunotherapy, 2010 - Taylor & Francis
The use of dendritic cells (DCs) for tumor immunotherapy represents a powerful approach
for harnessing the patient's own immune system to eliminate tumor cells. However …

Dendritic cell immunotherapy

RL Sabado, N Bhardwaj - Annals of the New York Academy of …, 2013 - Wiley Online Library
The US Food and Drug Administration's approval of the first cell‐based immunotherapy has
rejuvenated interest in the field. Early clinical trials have established the ability of dendritic …

Dendritic cells in cancer immunotherapy

A Vulink, KJ Radford, C Melief, DNJ Hart - Advances in cancer research, 2008 - Elsevier
Since their discovery, there has been significant progress in the understanding of dendritic
cell (DC) biology. Their capacity for priming an immune response against pathogens and …

The evolving role of dendritic cells in cancer therapy

EJ Ilett, RJD Prestwich, AA Melcher - Expert Opinion on Biological …, 2010 - Taylor & Francis
Importance of the field: Dendritic cells (DC) are a clear choice for use in cancer
immunotherapy, and much research has focused on generating DC for clinical use …

The use of dendritic cells in cancer immunotherapy

A Nencioni, F Grünebach, SM Schmidt… - Critical reviews in …, 2008 - Elsevier
Cancer immunotherapy aims at eliciting an immune response directed against tumor
antigens to help fight off residual tumor cells and thereby improve survival and quality of life …

Trial watch: Dendritic cell-based interventions for cancer therapy

L Galluzzi, L Senovilla, E Vacchelli, A Eggermont… - …, 2012 - Taylor & Francis
Dendritic cells (DCs) occupy a central position in the immune system, orchestrating a wide
repertoire of responses that span from the development of self-tolerance to the elicitation of …

Personalized dendritic cell-based tumor immunotherapy

N Janikashvili, N Larmonier, E Katsanis - Immunotherapy, 2010 - Taylor & Francis
Advances in the understanding of the immunoregulatory functions of dendritic cells (DCs) in
animal models and humans have led to their exploitation as anticancer vaccines. Although …

Immunotherapy with dendritic cells for cancer

A Ballestrero, D Boy, E Moran, G Cirmena… - Advanced drug delivery …, 2008 - Elsevier
Dendritic cells are professional antigen-presenting cells with a key role in both immunity
induction and tolerance maintenance. Dendritic cells are highly specialized in antigen …

Cancer immunotherapy via dendritic cells

K Palucka, J Banchereau - Nature Reviews Cancer, 2012 - nature.com
Cancer immunotherapy attempts to harness the power and specificity of the immune system
to treat tumours. The molecular identification of human cancer-specific antigens has allowed …

Dendritic cells: a critical player in cancer therapy?

AK Palucka, H Ueno, J Fay… - Journal of …, 2008 - journals.lww.com
Cancer immunotherapy seeks to mobilize a patient's immune system for therapeutic benefit.
It can be passive, that is, transfer of immune effector cells (T cells) or proteins (antibodies), or …