Oxygen consumption during oxygenated hypothermic perfusion as a measure of donor organ viability

L Bunegin, GP Tolstykh, JF Gelineau, AB Cosimi… - ASAIO …, 2013 - journals.lww.com
Hypothermic machine perfusion (HMP) for the preservation of kidneys, recovered from
extended criteria organ donors (ECDs), presents the opportunity for assessing ex vivo …

Oxygen consumption by warm ischemia-injured porcine kidneys in hypothermic static and machine preservation

J Kaminski, PO Delpech, S Kaaki-Hosni… - Journal of Surgical …, 2019 - Elsevier
Static cold storage (SCS) and hypothermic machine perfusion (HMP) are currently standard
methods for renal grafts clinical preservation. Both methods are predominantly implemented …

[HTML][HTML] Brief O2 uploading during continuous hypothermic machine perfusion is simple yet effective oxygenation method to improve initial kidney function in a porcine …

T Darius, M Vergauwen, T Smith, I Gerin, V Joris… - American journal of …, 2020 - Elsevier
With oxygenation proposed as a resuscitative measure during hypothermic models of
preservation, the aim of this study was to evaluate the optimal start time of oxygenation …

Influence of oxygen concentration during hypothermic machine perfusion on porcine kidneys from donation after circulatory death

DP Hoyer, A Gallinat, S Swoboda… - …, 2014 - journals.lww.com
Background Hypothermic machine perfusion (HMP) for preservation led to compelling
success for outcomes of renal transplantation. Application of different concentrations of …

Effects of oxygen during long-term hypothermic machine perfusion in a porcine model of kidney donation after circulatory death

LH Venema, A Brat, C Moers, NA't Hart, RJ Ploeg… - …, 2019 - journals.lww.com
Background. Hypothermic machine perfusion (HMP) has become standard care in many
center's to preserve kidneys donated after circulatory death (DCD). Despite a significant …

Comparison of normothermic and hypothermic perfusion in porcine kidneys donated after cardiac death

MF Blum, Q Liu, B Soliman, P Dreher… - Journal of Surgical …, 2017 - Elsevier
Background Normothermic machine perfusion (NMP) is an alternative strategy for
preserving kidneys donated after cardiac death (DCD). The relative efficacy of prolonged …

Role of oxygenation in hypothermic machine perfusion of kidneys from heart beating donors

A Gallinat, A Paul, P Efferz, B Lüer, S Swoboda… - …, 2012 - journals.lww.com
Dynamic preservation of organ grafts by hypothermic machine perfusion (HMP) has
regained broader interest to provide better outcome after transplantation. One pivotal aspect …

The effects of oxygenation on ex vivo kidneys undergoing hypothermic machine perfusion

K Patel, TB Smith, DAH Neil, A Thakker… - …, 2019 - journals.lww.com
Background Supplemental oxygenation of the standard hypothermic machine perfusion
(HMP) circuit has the potential to invoke favorable changes in metabolism, optimizing …

Oxygen supplementation supports energy production during hypothermic machine perfusion in a model of donation after circulatory death donors

SA Hosgood, ML Nicholson - Transplantation, 2019 - journals.lww.com
Organ preservation has historically relied on the concept that by reducing the temperature to
4 C, cellular metabolism is reduced to approximately 10% of normal. 1 Therefore, it is …

Improved kidney graft function after preservation using a novel hypothermic machine perfusion device

MHJ Maathuis, S Manekeller, A van der Plaats… - Annals of …, 2007 - journals.lww.com
Objective: To study graft function and ischemia/reperfusion injury of porcine kidneys after
preservation with the new Groningen Machine Perfusion (GMP) system versus static cold …