Understanding the molecular features responsible for the plasma kinetics of surface-
modified polyamido amine (PAMAM) dendrimers is critical to explore novel biomedical …

The surface charge of dendrimers is one of the key factors that determine their use in
nanomedicine. Generation 5 poly (amido amine) dendrimers (G5 PAMAM) encapsulating …

Improving the oral bioavailability of therapeutic compounds remains a challenging area of
research. Polyamidoamine (PAMAM) dendrimers are promising candidates for oral drug …

Surface-modified PAMAM dendrimers have important applications in drug delivery, yet a
gap remains about the role that surface functionalization plays on their cell internalization …

Abstract Poly (amidoamine)(PAMAM) dendrimers are a novel class of spherical, well-
designed branching polymers with interior cavities and abundant terminal groups on the …

Poly (amidoamine)(PAMAM) dendrimers have been proposed for a variety of biomedical
applications and are increasingly studied as model nanomaterials for such use. The …

BACKGROUND: Polyamidoamine (PAMAM) dendrimers have been investigated for
decades and currently applied in various areas throughout nanomedicine, including gene …

Dendrimers are global macromolecules with promising biomedical application. In order to
investigate their blood compatibility, different generations of polyamidoamine (PAMAM) …

Polyamidoamine (PAMAM) dendrimers are extensively researched as potential drug
delivery system thanks to their desirable features such as controlled and stable structures …

Carboplatin (CAR) is a second generation platinum-based compound emerging as one of
the most widely used anticancer drugs to treat a variety of tumors. In an attempt to address …