Twenty-five-year outbreak of Pseudomonas aeruginosa infecting individuals with cystic fibrosis: identification of the prairie epidemic strain

MD Parkins, BA Glezerson, CD Sibley… - Journal of clinical …, 2014 - Am Soc Microbiol
Transmissible strains of Pseudomonas aeruginosa have been described for cystic fibrosis
(CF) and may be associated with a worse prognosis. Using a comprehensive strain biobank …

Transmissible strains of Pseudomonas aeruginosa in cystic fibrosis lung infections

JL Fothergill, MJ Walshaw… - European Respiratory …, 2012 - Eur Respiratory Soc
Pseudomonas aeruginosa chronic lung infections are the major cause of morbidity and
mortality associated with cystic fibrosis. For many years, the consensus was that cystic …

Epidemiology, biology, and impact of clonal Pseudomonas aeruginosa infections in cystic fibrosis

MD Parkins, R Somayaji, VJ Waters - Clinical microbiology …, 2018 - Am Soc Microbiol
Chronic lower airway infection with Pseudomonas aeruginosa is a major contributor to
morbidity and mortality in individuals suffering from the genetic disease cystic fibrosis (CF) …

[HTML][HTML] Molecular Epidemiology of Chronic Pseudomonas aeruginosa Airway Infections in Cystic Fibrosis

N Cramer, L Wiehlmann, O Ciofu, S Tamm, N Høiby… - PloS one, 2012 - journals.plos.org
Background/Methods The molecular epidemiology of the chronic airway infections with
Pseudomonas aeruginosa in individuals with cystic fibrosis (CF) was investigated by cross …

[HTML][HTML] Persistence and Microevolution of Pseudomonas aeruginosa in the Cystic Fibrosis Lung: A Single-Patient Longitudinal Genomic Study

I Bianconi, S D'Arcangelo, A Esposito… - Frontiers in …, 2019 - frontiersin.org
Background: During its persistence in cystic fibrosis (CF) airways, P. aeruginosa develops a
series of phenotypic changes by the accumulation of pathoadaptive mutations. A better …

Molecular Epidemiology and Dynamics of Pseudomonas aeruginosa Populations in Lungs of Cystic Fibrosis Patients

L Jelsbak, HK Johansen, AL Frost… - Infection and …, 2007 - Am Soc Microbiol
The ability to establish lifelong persistent infections is a fundamental aspect of the
interactions between many pathogenic microorganisms and their mammalian hosts. One …

[HTML][HTML] Pseudomonas aeruginosa Exhibits Frequent Recombination, but Only a Limited Association between Genotype and Ecological Setting

TJ Kidd, SR Ritchie, KA Ramsay, K Grimwood, SC Bell… - 2012 - journals.plos.org
Pseudomonas aeruginosa is an opportunistic pathogen and an important cause of infection,
particularly amongst cystic fibrosis (CF) patients. While specific strains capable of patient-to …

Increased morbidity associated with chronic infection by an epidemic Pseudomonas aeruginosa strain in CF patients

M Al-Aloul, J Crawley, C Winstanley, CA Hart… - Thorax, 2004 - thorax.bmj.com
Background: Chronic pulmonary infection with transmissible Pseudomonas aeruginosa
strains in individuals with cystic fibrosis (CF) has been reported, raising issues of cross …

Pseudomonas aeruginosa adaptation and diversification in the non-cystic fibrosis bronchiectasis lung

Y Hilliam, MP Moore, IL Lamont, D Bilton… - European …, 2017 - Eur Respiratory Soc
To characterise Pseudomonas aeruginosa populations during chronic lung infections of non-
cystic fibrosis bronchiectasis patients, we used whole-genome sequencing to 1) assess the …

Phenotypic characterization of an international Pseudomonas aeruginosa reference panel: strains of cystic fibrosis (CF) origin show less in vivo virulence than non …

L Cullen, R Weiser, T Olszak, RF Maldonado… - …, 2015 - microbiologyresearch.org
Pseudomonas aeruginosa causes chronic lung infections in people with cystic fibrosis (CF)
and acute opportunistic infections in people without CF. Forty-two P. aeruginosa strains from …