Congenital heart disease is the most frequent birth defect and the leading cause of death for
the fetus and in the first year of life. The wide phenotypic diversity of congenital heart defects …

Congenital heart disease is the commonest malformation in humans and contributes greatly
to the burden of disease in infancy. Increasingly, developmental origins are also implicated …

Developmental heart disorders are the most common of all human birth defects and occur in
nearly one percent of the population. Survivors of congenital heart malformations are an …

Congenital heart disease likely results from a complex mixture of environmental and genetic
factors. Recent work has elucidated rare single gene mutations that cause a variety of …

In 2014, an extensive review discussing the major steps of cardiac development focusing on
growth, formation of primary and chamber myocardium and the development of the cardiac …

Congenital heart defects are common in humans, but the underlying basis for these defects
is not well understood. It has been clear that abnormal heart development is at the root of …

Cardiovascular malformations are the most common type of birth defect and result in
significant mortality worldwide. The etiology for the majority of these anomalies remains …

Molecular and genetic studies around the turn of this century have revolutionized the field of
cardiac development. We now know that the primary heart tube, as seen in the early embryo …

The genetic basis of congenital heart disease, an important form of cardiovascular disease
in the young, is being increasingly recognized. Using a combination of human molecular …

Congenital heart diseases (CHDs) are recognized as the most common type of birth
malformations. Although recent advances in pre-and neonatal diagnosis as well as in …