Dissecting the relationship between neuropsychiatric and neurodegenerative disorders

R Gupta, D Advani, D Yadav, RK Ambasta… - Molecular …, 2023 - Springer
Neurodegenerative diseases (NDDs) and neuropsychiatric disorders (NPDs) are two
common causes of death in elderly people, which includes progressive neuronal cell death …

Gut–brain axis as a pathological and therapeutic target for neurodegenerative disorders

ARL Toledo, GR Monroy, FE Salazar, JY Lee… - International Journal of …, 2022 - mdpi.com
Human lifestyle and dietary behaviors contribute to disease onset and progression.
Neurodegenerative diseases (NDDs), considered multifactorial disorders, have been …

Neuroinflammation as a common denominator of complex diseases (cancer, diabetes type 2, and neuropsychiatric disorders)

S Asslih, O Damri, G Agam - International Journal of Molecular Sciences, 2021 - mdpi.com
The term neuroinflammation refers to inflammation of the nervous tissue, in general, and in
the central nervous system (CNS), in particular. It is a driver of neurotoxicity, it is detrimental …

[HTML][HTML] Therapeutics for neurodegenerative diseases by targeting the gut microbiome: from bench to bedside

YY Ma, X Li, JT Yu, YJ Wang - Translational Neurodegeneration, 2024 - Springer
The aetiologies and origins of neurodegenerative diseases, such as Alzheimer's disease
(AD), Parkinson's disease (PD), amyotrophic lateral sclerosis (ALS) and Huntington's …

[HTML][HTML] World digestive health day: investigating the link between neurodegenerative disease and gut microbiota

S Ghosh, S Dhungel, MF Shaikh… - Frontiers in Aging …, 2024 - frontiersin.org
Neurodegenerative diseases (NDs), such as Alzheimer's and Parkinson's disease (PD), are
debilitating conditions that affect millions of people worldwide (Ghosh et al., 2020) …

[HTML][HTML] A review of the preclinical and clinical studies on the role of the gut microbiome in aging and neurodegenerative diseases and its modulation

HM Hashim, S Makpol - Frontiers in Cellular Neuroscience, 2022 - frontiersin.org
As the world population ages, the burden of age-related health problems grows, creating a
greater demand for new novel interventions for healthy ageing. Advancing ageing is related …

Brain Aging and Gut–Brain Axis

MH Mohajeri - Nutrients, 2019 - mdpi.com
In the last decade, the microbiome in general and the gut microbiome in particular have
been associated not only to brain development and function, but also to the pathophysiology …

[HTML][HTML] Towards early detection of neurodegenerative diseases: A gut feeling

S Makdissi, BD Parsons, F Di Cara - Frontiers in cell and …, 2023 - frontiersin.org
The gastrointestinal tract communicates with the nervous system through a bidirectional
network of signaling pathways called the gut-brain axis, which consists of multiple …

The gut microbiome alterations and inflammation-driven pathogenesis of Alzheimer's disease—a critical review

M Sochocka, K Donskow-Łysoniewska, BS Diniz… - Molecular …, 2019 - Springer
One of the most important scientific discoveries of recent years was the disclosure that the
intestinal microflora takes part in bidirectional communication between the gut and the brain …

[HTML][HTML] The interplay between the gut-brain axis and the microbiome: A perspective on psychiatric and neurodegenerative disorders

Y Bashir, AU Khan - Frontiers in Neuroscience, 2022 - frontiersin.org
What is the effect of our gut microbial flora on brain? Does the gut microbiome have any role
in the causation of psychiatric and neurodegenerative diseases? Does the effect of gut …