From organic and inorganic phosphates to valvular and vascular calcifications
M Bäck, JB Michel - Cardiovascular Research, 2021 - academic.oup.com
Calcification of the arterial wall and valves is an important part of the pathophysiological
process of peripheral and coronary atherosclerosis, aortic stenosis, ageing, diabetes, and …
process of peripheral and coronary atherosclerosis, aortic stenosis, ageing, diabetes, and …
Vascular calcification: key roles of phosphate and pyrophosphate
R Villa-Bellosta - International Journal of Molecular Sciences, 2021 - mdpi.com
Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are
the leading cause of morbimortality in Western society. Both pathologies are frequently …
the leading cause of morbimortality in Western society. Both pathologies are frequently …
New insights into endogenous mechanisms of protection against arterial calcification
R Villa-Bellosta - Atherosclerosis, 2020 - Elsevier
Cardiovascular complications due to accelerated atherosclerosis and arterial stiffening are
the leading cause of morbidity and mortality in the Western society. Both pathologies are …
the leading cause of morbidity and mortality in the Western society. Both pathologies are …
The biology of vascular calcification
Vascular calcification (VC), characterized by different mineral deposits (ie, carbonate apatite,
whitlockite and hydroxyapatite) accumulating in blood vessels and valves, represents a …
whitlockite and hydroxyapatite) accumulating in blood vessels and valves, represents a …
Tissue non-specific alkaline phosphatase and vascular calcification: a potential therapeutic target
D Azpiazu, S Gonzalo… - Current cardiology …, 2019 - ingentaconnect.com
Vascular calcification is a pathologic phenomenon consisting of calcium phosphate crystal
deposition in the vascular walls. Vascular calcification has been found to be a risk factor for …
deposition in the vascular walls. Vascular calcification has been found to be a risk factor for …
Regulation of vascular calcification: roles of phosphate and osteopontin
Vascular calcification is prevalent in aging as well as a number of pathological conditions,
and it is now recognized as a strong predictor of cardiovascular events in the general …
and it is now recognized as a strong predictor of cardiovascular events in the general …
[HTML][HTML] Novel insights into vascular calcification
M Ketteler, C Giachelli - Kidney International, 2006 - Elsevier
Vascular calcification is not just a hallmark of uremic arterio-and atherosclerosis, but also a
significant cardiovascular risk factor in patients with chronic kidney disease. In contrast to the …
significant cardiovascular risk factor in patients with chronic kidney disease. In contrast to the …
Synthesis of extracellular pyrophosphate increases in vascular smooth muscle cells during phosphate-induced calcification
R Villa-Bellosta - Arteriosclerosis, thrombosis, and vascular biology, 2018 - Am Heart Assoc
Objective—Hydroxyapatite deposition on the medial layer of the aortic walls is the hallmark
of vascular calcification and the most common complication in aging individuals and in …
of vascular calcification and the most common complication in aging individuals and in …
Phosphate and cardiovascular disease beyond chronic kidney disease and vascular calcification
S Disthabanchong - International journal of nephrology, 2018 - Wiley Online Library
Phosphate is essential for life but its accumulation can be detrimental. In end‐stage renal
disease, widespread vascular calcification occurs as a result of chronic phosphate load. The …
disease, widespread vascular calcification occurs as a result of chronic phosphate load. The …
[HTML][HTML] Pyrophosphate deficiency in vascular calcification
R Villa-Bellosta, WC O'Neill - Kidney international, 2018 - Elsevier
Pathologic cardiovascular calcification is associated with a number of conditions and is a
common complication of chronic kidney disease. Because ambient calcium and phosphate …
common complication of chronic kidney disease. Because ambient calcium and phosphate …
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