Mitochondria are the primary source of energy production and are implicated in a wide
range of biological processes in most eukaryotic cells. Skeletal muscle heavily relies on …

Mitochondrial dysfunction in skeletal muscle fibres occurs with both healthy aging and a
range of neuromuscular diseases. The impact of mitochondrial dysfunction in skeletal …

The skeletal muscle is one of the largest organs in the mammalian body. Its remarkable
ability to swiftly shift its substrate selection allows other organs like the brain to choose their …

Mitochondrial activity warrants energy supply to oxidative myofibres to sustain endurance
workload. The maintenance of mitochondrial homeostasis is ensured by the control of fission …

Mitochondria are fascinating organelles regulating many critical cellular processes for
skeletal muscle physiology. Indeed, they play central roles in muscle cell metabolism …

Skeletal muscle is a tissue with a low mitochondrial content under basal conditions, but it is
responsive to acute increases in contractile activity patterns (ie exercise) which initiate the …

Mitochondria are critical organelles responsible for regulating the metabolic status of
skeletal muscle. These organelles exhibit remarkable plasticity by adapting their volume …

Background Maintaining skeletal muscle mitochondrial content and function is important for
sustained health throughout the lifespan. Exercise stimulates important key stress signals …

Background While there is agreement that exercise is a powerful stimulus to increase both
mitochondrial function and content, we do not know the optimal training stimulus to …

Mitochondria are characterized by its pivotal roles in managing energy production, reactive
oxygen species, and calcium, whose aging‐related structural and functional deteriorations …