[HTML][HTML] Functional imaging for assessing regional lung ventilation in preclinical and clinical research

D Karmali, M Sowho, S Bose, J Pearce… - Frontiers in …, 2023 - frontiersin.org
Dynamic heterogeneity in lung ventilation is an important measure of pulmonary function
and may be characteristic of early pulmonary disease. While standard indices like …

Lung functional imaging

S Bayat, J Wild, T Winkler - Breathe, 2023 - Eur Respiratory Soc
Pulmonary functional imaging modalities such as computed tomography, magnetic
resonance imaging and nuclear imaging can quantitatively assess regional lung functional …

[HTML][HTML] Quantification of heterogeneity in lung disease with image-based pulmonary function testing

CS Stahr, CR Samarage, M Donnelley, N Farrow… - Scientific reports, 2016 - nature.com
Computed tomography (CT) and spirometry are the mainstays of clinical pulmonary
assessment. Spirometry is effort dependent and only provides a single global measure that …

Pulmonary functional imaging: Part 2—state-of-the-Art clinical applications and opportunities for improved patient care

WB Gefter, KS Lee, ML Schiebler, G Parraga, JB Seo… - Radiology, 2021 - pubs.rsna.org
Pulmonary functional imaging may be defined as the regional quantification of lung function
by using primarily CT, MRI, and nuclear medicine techniques. The distribution of pulmonary …

Functional lung imaging: emerging methods to visualize regional pulmonary physiology1

WB Gefter, H Hatabu - Academic Radiology, 2003 - academicradiology.org
This is a particularly exciting era for thoracic imaging. Rapidly evolving technical advances
in CT and MR are enabling increasingly sophisticated capabilities for pulmonary functional …

Pulmonary functional imaging: Part 1—state-of-the-art technical and physiologic underpinnings

Y Ohno, JB Seo, G Parraga, KS Lee, WB Gefter… - Radiology, 2021 - pubs.rsna.org
Over the past few decades, pulmonary imaging technologies have advanced from chest
radiography and nuclear medicine methods to high-spatial-resolution or low-dose chest CT …

Preclinical four-dimensional functional lung imaging and quantification of regional airflow: a new standard in lung function evaluation in murine models

K Asosingh, M Frimel, V Zlojutro, D Grant… - American Journal of …, 2022 - atsjournals.org
The current standard for lung function evaluation in murine models is based on forced
oscillation technology, which provides a measure of the total airway function but cannot …

What can computed tomography and magnetic resonance imaging tell us about ventilation?

BA Simon, DW Kaczka, AA Bankier… - Journal of Applied …, 2012 - journals.physiology.org
This review provides a summary of pulmonary functional imaging approaches for
determining pulmonary ventilation, with a specific focus on multi-detector x-ray computed …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Functional imaging of the airways

JG Goldin, DR Aberle - Journal of thoracic imaging, 1997 - journals.lww.com
The use of traditional pulmonary function tests (PFT) to assess airflow obstruction is limited
by the fact that these measurements are global and can neither express the potential …