State of the Art. A structural and functional assessment of the lung via multidetector-row computed tomography: phenotyping chronic obstructive pulmonary disease
EA Hoffman, BA Simon, G McLennan - Proceedings of the American …, 2006 - atsjournals.org
With advances in multidetector-row computed tomography (MDCT), it is now possible to
image the lung in 10 s or less and accurately extract the lungs, lobes, and airway tree to the …
image the lung in 10 s or less and accurately extract the lungs, lobes, and airway tree to the …
Longitudinal micro-CT provides biomarkers of lung disease that can be used to assess the effect of therapy in preclinical mouse models, and reveal compensatory …
G Vande Velde, J Poelmans… - Disease models & …, 2016 - journals.biologists.com
In vivo lung micro-computed tomography (micro-CT) is being increasingly embraced in
pulmonary research because it provides longitudinal information on dynamic disease …
pulmonary research because it provides longitudinal information on dynamic disease …
Synchrotron-based dynamic computed tomography of tissue motion for regional lung function measurement
During breathing, lung inflation is a dynamic process involving a balance of mechanical
factors, including trans-pulmonary pressure gradients, tissue compliance and airway …
factors, including trans-pulmonary pressure gradients, tissue compliance and airway …
Quantification of dual-energy CT-derived functional parameters as potential imaging markers for progression of idiopathic pulmonary fibrosis
SC Scharm, J Vogel-Claussen, C Schaefer-Prokop… - European …, 2021 - Springer
Objectives The individual course of disease in idiopathic pulmonary fibrosis (IPF) is highly
variable. Assessment of disease activity and prospective estimation of disease progression …
variable. Assessment of disease activity and prospective estimation of disease progression …
Functional imaging of the lungs with gas agents
This review focuses on the state‐of‐the‐art of the three major classes of gas contrast agents
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
used in magnetic resonance imaging (MRI)—hyperpolarized (HP) gas, molecular oxygen …
Measuring lung function in airways diseases: current and emerging techniques
Chronic airways diseases, including asthma, COPD and cystic fibrosis, cause significant
morbidity and mortality and are associated with high healthcare expenditure, in the UK and …
morbidity and mortality and are associated with high healthcare expenditure, in the UK and …
Imaging for lung physiology: what do we wish we could measure?
HT Robertson, RB Buxton - Journal of applied physiology, 2012 - journals.physiology.org
The role of imaging as a tool for investigating lung physiology is growing at an accelerating
pace. Looking forward, we wished to identify unresolved issues in lung physiology that might …
pace. Looking forward, we wished to identify unresolved issues in lung physiology that might …
Parametric response mapping monitors temporal changes on lung CT scans in the subpopulations and intermediate outcome measures in COPD Study (SPIROMICS)
JL Boes, BA Hoff, M Bule, TD Johnson, A Rehemtulla… - Academic radiology, 2015 - Elsevier
Rationale and Objectives The longitudinal relationship between regional air trapping and
emphysema remains unexplored. We have sought to demonstrate the utility of parametric …
emphysema remains unexplored. We have sought to demonstrate the utility of parametric …
2D ultrashort echo‐time functional lung imaging
A Balasch, P Metze, K Stumpf, M Beer… - Journal of Magnetic …, 2020 - Wiley Online Library
Background Imaging of the lung by MRI is challenging due to the intrinsic low proton density
and rapid T2* relaxation. MRI methods providing lung parenchyma and function are in …
and rapid T2* relaxation. MRI methods providing lung parenchyma and function are in …
Quantification of lung function on CT images based on pulmonary radiomic filtering
Purpose To develop a radiomics filtering technique for characterizing spatial‐encoded
regional pulmonary ventilation information on lung computed tomography (CT). Methods …
regional pulmonary ventilation information on lung computed tomography (CT). Methods …