Non-invasive imaging of regional lung function using x-ray computed tomography

BA Simon - Journal of clinical monitoring and computing, 2000 - Springer
The use of imaging technologies has progressed beyond the depiction of anatomic
abnormalities to providing non-invasive regional structure and functional information in …

Dismantling the pathophysiology of asthma using imaging

GG King, CE Farrow… - European Respiratory …, 2019 - Eur Respiratory Soc
Asthma remains an important disease worldwide, causing high burden to patients and
healthcare systems and presenting a need for better management and ultimately prevention …

Imaging advances in chronic obstructive pulmonary disease. Insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study

SP Bhatt, GR Washko, EA Hoffman… - American journal of …, 2019 - atsjournals.org
The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …

Lung imaging

S Ley - European Respiratory Review, 2015 - Eur Respiratory Soc
Imaging of the lung is a mainstay of respiratory medicine. It provides local information about
morphology and function of the lung parenchyma that is unchallenged by other noninvasive …

Assessing and treating small airways disease in asthma and chronic obstructive pulmonary disease

OS Usmani, PJ Barnes - Annals of medicine, 2012 - Taylor & Francis
Asthma and chronic obstructive pulmonary disease (COPD) are chronic inflammatory
disorders of the respiratory tract that are characterized by airflow limitation. They are distinct …

A respiratory‐gated micro‐CT comparison of respiratory patterns in free‐breathing and mechanically ventilated rats

NL Ford, L McCaig, A Jeklin, JF Lewis… - Physiological …, 2017 - Wiley Online Library
In this study, we aim to quantify the differences in lung metrics measured in free‐breathing
and mechanically ventilated rodents using respiratory‐gated micro‐computed tomography …

Local heterogeneity of normal lung parenchyma and small airways disease are associated with COPD severity and progression

AJ Bell, R Pal, WW Labaki, BA Hoff, JM Wang… - Respiratory …, 2024 - Springer
Background Small airways disease (SAD) is a major cause of airflow obstruction in COPD
patients and has been identified as a precursor to emphysema. Although the amount of SAD …

X-Ray based Lung Function measurement–a sensitive technique to quantify lung function in allergic airway inflammation mouse models

C Dullin, MA Markus, E Larsson, G Tromba… - Scientific Reports, 2016 - nature.com
In mice, along with the assessment of eosinophils, lung function measurements, most
commonly carried out by plethysmography, are essential to monitor the course of allergic …

Feasibility of quantitative regional ventilation and perfusion mapping with phase‐resolved functional lung (PREFUL) MRI in healthy volunteers and COPD, CTEPH …

A Voskrebenzev, M Gutberlet, F Klimeš… - Magnetic resonance …, 2018 - Wiley Online Library
Purpose In this feasibility study, a phase‐resolved functional lung imaging postprocessing
method for extraction of dynamic perfusion (Q) and ventilation (V) parameters using a …

Quantifying lung morphology with respiratory-gated micro-CT in a murine model of emphysema

NL Ford, EL Martin, JF Lewis… - Physics in Medicine …, 2009 - iopscience.iop.org
Non-invasive micro-CT imaging techniques have been developed to investigate lung
structure in free-breathing rodents. In this study, we investigate the utility of retrospectively …