Within pulmonary research, the development of mouse models has provided insight into
disease development, progression, and treatment. Structural phenotypes of the lung in …

With the incidence of respiratory diseases increasing throughout the world, new therapies
are needed. This review provides a short overview of different imaging techniques of interest …

To effectively diagnose, monitor and treat respiratory disease clinicians should be able to
accurately assess the spatial distribution of airflow across the fine structure of lung. This …

Pulmonary computational fluid dynamics models require that three-dimensional images be
acquired over multiple points in the dynamic breathing cycle without breath holds or …

Measurement of ventilation heterogeneity with the multiple-breath nitrogen washout (MBW)
is usually performed using controlled breathing with a fixed tidal volume and breathing …

Multidetector row computed tomography (MDCT) is increasingly taking a central role in
identifying subphenotypes within chronic obstructive pulmonary disease (COPD), asthma …

Objectives To evaluate the feasibility of using automatic quantitative analysis of breath hold
gated micro-CT images to detect and monitor disease in a mouse model of chronic …

Rationale and Objectives. Efforts to establish a quantitative approach to the computed
tomography (CT)-based characterization of the lung parenchyma in interstitial lung disease …

Rationale and Objectives Small airways disease (SAD) and emphysema are significant
components of chronic obstructive pulmonary disease (COPD), a heterogenous disease …

Changes in the shape of the lung during breathing determine the movement of airways and
alveoli, and thus impact airflow dynamics. Modeling airflow dynamics in health and disease …