Imaging of regional ventilation: Is CT ventilation imaging the answer? A systematic review of the validation data

F Hegi-Johnson, D de Ruysscher, P Keall… - Radiotherapy and …, 2019 - Elsevier
Abstract Computed Tomography Ventilation Imaging (CTVI) is an experimental imaging
modality that derives regional lung function information from non-contrast respiratory …

Tomographic in vivo microscopy for the study of lung physiology at the alveolar level

G Lovric, R Mokso, F Arcadu, I Vogiatzis Oikonomidis… - Scientific reports, 2017 - nature.com
Lungs represent the essential part of the mammalian respiratory system, which is reflected in
the fact that lung failure still is one of the leading causes of morbidity and mortality …

Seven pillars of small airways disease in asthma and COPD: supporting opportunities for novel therapies

OS Usmani, MLK Han, DA Kaminsky, J Hogg… - Chest, 2021 - Elsevier
Identification of pathologic changes in early and mild obstructive lung disease has shown
the importance of the small airways and their contribution to symptoms. Indeed, significant …

Functional respiratory imaging provides novel insights into the long-term respiratory sequelae of bronchopulmonary dysplasia

K Vanhaverbeke, M Slaats, M Al-Nejar… - European …, 2021 - Eur Respiratory Soc
Rationale Bronchopulmonary dysplasia (BPD) is a common complication of preterm birth.
Lung function and imaging are classically used to assess BPD. Functional respiratory …

Dynamic airway constriction in rats: heterogeneity and response to deep inspiration

TKN Phung, SE Sinclair, P Makena… - … of Physiology-Lung …, 2019 - journals.physiology.org
Airway narrowing due to hyperresponsiveness severely limits gas exchange in patients with
asthma. Imaging studies in humans and animals have shown that bronchoconstriction …

CT-based local distribution metric improves characterization of COPD

BA Hoff, E Pompe, S Galbán, DS Postma… - Scientific reports, 2017 - nature.com
Parametric response mapping (PRM) of paired CT lung images has been shown to improve
the phenotyping of COPD by allowing for the visualization and quantification of non …