Diabetic nephropathy (DN) is one of the most important renal complications associated with
diabetes, and the mechanisms are yet to be fully understood. To date, few studies have …

Background. Diabetic nephropathy (DN) is one of the most common microvascular
complications of diabetes and is the leading cause of end‐stage renal disease (ESRD) and …

BACKGROUND Diabetic nephropathy is a major risk of end-stage kidney disease. Many
complex factors relate to the progression of diabetic nephropathy. Using nonobese type 2 …

Oxidative stress and abnormal lipid metabolism in diabetes can trigger renal lipotoxicity,
extending to diabetic nephropathy. Vitamin D 3 has been known to be involved in lipid …

Abstract We investigated whether 1, 25-dihydroxy-vitamin D 3 (1, 25 (OH) 2 D 3) could
improve early diabetic nephropathy through the DNA-damage-inducible transcript …

Background It is well established that the activation of the renin–angiotensin system (RAS)
and the oxidative stress caused by hyperglycemia are major mediators of the development …

Abstract Background Type 1 diabetes (T1D) is accompanied by numerous side effects,
including renal dysfunction. Mounting evidence suggests that overactivation of nuclear factor …

Introduction Trace element metabolism disorders are often secondary to disorders of
glucose metabolism in diabetes. Although 1α, 25-dihydroxyvitamin D3 [1, 25 (OH) 2D3] …

Purpose The study aimed to investigate the potential nephroprotective effects of vitamin D3
in metabolic syndrome (MetS) and the molecular basis of the underlying mechanisms of its …

Oxidative stress may contribute to the pathogenesis of diabetic nephropathy (DN), although
the detailed mechanism of reactive oxygen species (ROS) regulation is still unclear. This …