Background: Genistein being a phytoestrogen imitates the characteristics of estrogen, which
can be useful to treat conditions by reducing the estrogen levels at the time of menopause …

Genistein can prevent tumorigenesis and reduce the incidence of diseases that are
dependent upon estrogen. Previous research, however, has shown that genistein can also …

Genistein is an isoflavonoid present in high quantities in soybeans. Possessing a wide
range of bioactives, it is being studied extensively for its tumoricidal effects. Investigations …

Genistein is a well known protein tyrosine kinase inhibitor. It is structurally similar to 17beta-
estradiol and exerts antiestrogenic effects. It also affects the signal transduction components …

Genistein is a major isoflavone with known hormonal and tyrosine kinase-modulating
activities. Genistein has been shown to promote the growth of estrogen receptor positive …

Breast cancer (BC) is one of the most common malignancies in women. Although
widespread successful synthetic drugs are available, natural compounds can also be …

Genistein significantly inhibited cell growth (IC50 around 10 μM) of MCF-7, MDAMB-231 and
HBL-100 cell lines, but not of skin-derived fibroblasts and counteracted the growth …

Background Most breast cancers are estrogen dependent and were sensitive to endocrine
therapy, and genistein (GEN) shows strong affinity with human oestrogen receptor beta …

Genistein, a natural isoflavanoid phytoestrogen, is thought to be the active ingredient in soy
that possesses breast cancer preventive properties. The molecular mechanisms that are …

The estrogen receptor (ER) is a major target for the treatment of breast cancer cells.
Genistein, a soy isoflavone, possesses a structure similar to estrogen and can both mimic …