[HTML][HTML] Chemoprevention of Breast Cancer, Proteomic Discovery of Genistein Action in the Rat Mammary Gland–

C Rowell, DM Carpenter, CA Lamartiniere - The Journal of nutrition, 2005 - Elsevier
Genistein, the primary isoflavone component of soy, consumed in the diet during the
prepubertal period only, and the combined prepubertal and adult periods, suppresses …

Genistein induces G2/M cell cycle arrest via stable activation of ERK1/2 pathway in MDA-MB-231 breast cancer cells

Z Li, J Li, B Mo, C Hu, H Liu, H Qi, X Wang… - Proceedings of the VIIIth …, 2009 - Springer
Genistein is an isoflavonoid present in soybeans that exhibits anti-carcinogenic effect.
Several studies have shown that genistein can trigger G2/M cell cycle arrest and inhibit cell …

Mechanisms of cancer chemoprevention by soy isoflavone genistein

FH Sarkar, Y Li - Cancer and Metastasis Reviews, 2002 - Springer
Diet has been implicated to play an important role in cancers. Epidemiological studies have
revealed that Asians, who consume a traditional diet high in soy products, have relatively …

Understanding genistein in cancer: The “good” and the “bad” effects: A review

M Russo, GL Russo, M Daglia, PD Kasi, S Ravi… - Food chemistry, 2016 - Elsevier
Nowadays, diet and specific dietary supplements are seen as potential adjuvants to prevent
different chronic diseases, including cancer, or to ameliorate pharmacological therapies …

[PDF][PDF] A comprehensive anticancer molecular study for genistein the promising anticancer drug.

RR Hafidh - Journal of Contemporary Medical Sciences, 2017 - iasj.net
Objective Genistein a potent isoflavonoid isolated from dietary soybean with a wide range of
biological and therapeutic activities, particularly, in cancer prevention. The molecular …

[HTML][HTML] Genistein inhibits MDA-MB-231 triple-negative breast cancer cell growth by inhibiting NF-κB activity via the Notch-1 pathway

H Pan, W Zhou, W He, X Liu… - International …, 2012 - spandidos-publications.com
Genistein (Gen) has been reported as a protective factor against breast cancer. However,
the molecular mechanism by which Gen elicits its effects on triple-negative breast cancer …

[HTML][HTML] Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway

P Fan, S Fan, H Wang, J Mao, Y Shi… - Stem cell research & …, 2013 - Springer
Introduction The existence of breast cancer stem-like cells (BCSCs) has profound
implications for cancer prevention. Genistein, a predominant isoflavone found in soy …

Genistein: an integrative overview of its mode of action, pharmacological properties, and health benefits

J Sharifi-Rad, C Quispe, M Imran, A Rauf… - Oxidative medicine …, 2021 - Wiley Online Library
Genistein is an isoflavone first isolated from the brooming plant Dyer's Genista tinctoria L.
and is widely distributed in the Fabaceae family. As an isoflavone, mammalian genistein …

Inactivation of NF-κB by genistein is mediated via Akt signaling pathway in breast cancer cells

L Gong, Y Li, A Nedeljkovic-Kurepa, FH Sarkar - Oncogene, 2003 - nature.com
Genistein, a natural isoflavonoid found in soybean products, has been proposed to be
associated with a lower rate of breast cancer in Asian women. Studies from our laboratory …

Synergistic inhibitory effects of genistein and tamoxifen on human dysplastic and malignant epithelial breast cells in vitro

V Tanos, A Brzezinski, O Drize, N Strauss… - European Journal of …, 2002 - Elsevier
Objective: Genistein is a phytoestrogen with in vitro anticancerogenic activity. We examined
in vitro the effects of genistein alone, or in combination with estradiol and tamoxifen, on the …