Cellular stress is a fundamental component of age-associated disease. Cells experience
many forms of stress (oxidative, heavy metal, etc.), and as we age the burden of stress and …

Cellular stress is a fundamental component of age-associated disease. Cells experience
many forms of stress (oxidative, heavy metal, etc.), and as we age the burden of stress and …

The model species, Caenorhabditis elegans, has been used as a tool to probe for
mechanisms underlying numerous neurodegenerative diseases. This use has been …

Aging is primarily attributed to radical reactions, as hypothesized by the theory of oxidative
stress. The foremost objective presented in aging-related research is studying the effects of …

Aging is associated with progressive loss of cellular homeostasis resulting from intrinsic and
extrinsic challenges. Lack of a carefully designed, well-characterized, precise, translational …

Chronic stress can shorten lifespan and is a risk factor for a diverse range of aging-related
diseases. Despite the consistency of this relationship, it remains unclear how stress might …

Understanding basic mechanisms of aging holds great promise for developing interventions
that prevent or delay many age-related declines and diseases simultaneously to increase …

This chapter contains sections titled: Introduction Memory Impairment During Aging
Cognitive Aging in C. Elegans What Causes AMI? Other Factors that may Cause AMI …

Age/stage sensitivity is considered a significant factor in toxicity assessments. Previous
studies investigated cadmium (Cd) toxicosis in Caenorhabditis elegans, and a plethora of …

Exposure to chronic adverse conditions, and the resultant activation of the neurobiological
response cascade, has been associated with an increased risk of early onset of age-related …