Iron plays a critical role in survival and virulence of the opportunistic pathogen Aspergillus
fumigatus. Two transcription factors, the GATA-factor SreA and the bZip-factor HapX …

Iron is an essential but, in excess, toxic nutrient. Therefore, fungi evolved fine-tuned
mechanisms for uptake and storage of iron, such as the production of siderophores (low …

Aspergillus fumigatus, the most common airborne fungal pathogen of humans, employs two
high‐affinity iron uptake systems: iron uptake mediated by the extracellular siderophore …

Iron is essential for a wide range of cellular processes. Here we show that the bZIP-type
regulator HapX is indispensable for the transcriptional remodeling required for adaption to …

Siderophore biosynthesis by the highly lethal mould Aspergillus fumigatus is essential for
virulence, but non-existent in humans, presenting a rare opportunity to strategize …

The opportunistic fungal pathogen Aspergillus fumigatus adapts to iron limitation by
upregulation of iron uptake mechanisms including siderophore biosynthesis and …

Iron acquisition is crucial for virulence of the human pathogen Aspergillus fumigatus.
Previous studies indicated that this mold regulates iron uptake via both siderophores and …

To maintain iron homeostasis, fungi have to balance iron acquisition, storage, and utilization
to ensure sufficient supply and to avoid toxic excess of this essential trace element. As …

The airborne fungus Aspergillus fumigatus causes opportunistic infections in humans with
high mortality rates in immunocompromised patients. Previous work established that the …

Iron is an essential trace element that is limiting in most habitats including hosts for fungal
pathogens. Siderophores are iron-chelators synthesized by most fungal species for high …