Human models of migraine comprise an important tool for investigating the mechanisms
constituting a migraine attack. Once administration of calcitonin gene-related peptide …

With the approval of calcitonin gene-related peptide (CGRP) and CGRP receptor
monoclonal antibodies by the Federal Drug Administration, a new era in the treatment of …

Migraine sciences have witnessed tremendous advances in recent years. Pre-clinical and
clinical experimental models have contributed significantly to provide useful insights into the …

Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a
critical player in migraine pathophysiology. Excitement has grown regarding CGRP because …

Calcitonin gene-related peptide (CGRP) is a well-studied neuropeptide of relevance for
migraine pathophysiology. Jugular levels of CGRP are increased during migraine attacks …

Migraine is a highly prevalent headache disease that typically affects patients during their
most productive years. Despite significant progress in understanding the underlying …

Migraine is a highly prevalent, complex neurological disorder. The burden of disease and
the direct/indirect annual costs are enormous. Thus far, treatment options have been …

This article highlights the evidence behind the role of CGRP in migraine and the state of
CGRP-based mechanism treatment development. We present a summary of the evidence …

Migraine is considered as one of the most debilitating neurological disorders but the
success of the anti‐calcitonin gene‐related peptide (CGRP) therapies marks a new era in …

Migraine is a neurological disorder that manifests as a debilitating headache associated
with altered sensory perception. The neuropeptide calcitonin gene-related peptide (CGRP) …