The roles of nuclear receptors in cholesterol metabolism and reverse cholesterol transport in nonalcoholic fatty liver disease

Z Li, D Zheng, T Zhang, S Ruan, N Li, Y Yu… - Hepatology …, 2024 - journals.lww.com
As the most prevalent chronic liver disease globally, NAFLD encompasses a pathological
process that ranges from simple steatosis to NASH, fibrosis, cirrhosis, and HCC, closely …

Nuclear receptors and nonalcoholic fatty liver disease

MC Cave, HB Clair, JE Hardesty, KC Falkner… - … et Biophysica Acta (BBA …, 2016 - Elsevier
Nuclear receptors are transcription factors which sense changing environmental or
hormonal signals and effect transcriptional changes to regulate core life functions including …

Recent insights into hepatic lipid metabolism in non-alcoholic fatty liver disease (NAFLD)

G Musso, R Gambino, M Cassader - Progress in lipid research, 2009 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in
Western countries and is considered the hepatic manifestation of metabolic syndrome. The …

[HTML][HTML] Nuclear receptors and non-alcoholic fatty liver disease: An update

X Yang, FJ Gonzalez, M Huang, H Bi - Liver Research, 2020 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) has become the leading cause of chronic liver
disease in adults and children worldwide. The symptoms of NAFLD range from simple …

[HTML][HTML] The role of nuclear receptors in the pathogenesis and treatment of non-alcoholic fatty liver disease

Z Yang, A Danzeng, Q Liu, C Zeng, L Xu… - … Journal of Biological …, 2024 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is a global health burden closely linked to insulin
resistance, obesity, and type 2 diabetes. The complex pathophysiology of NAFLD involves …

[HTML][HTML] Nuclear receptors and transcriptional regulation in non-alcoholic fatty liver disease

Y Xiao, M Kim, MA Lazar - Molecular Metabolism, 2021 - Elsevier
Background As a result of a sedentary lifestyle and excess food consumption in modern
society, non-alcoholic fatty liver disease (NAFLD) characterized by fat accumulation in the …

[HTML][HTML] Recent insights on the role of cholesterol in non-alcoholic fatty liver disease

G Arguello, E Balboa, M Arrese, S Zanlungo - Biochimica et Biophysica …, 2015 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of hepatic
histopathological changes ranging from non-inflammatory intracellular fat deposition to non …

Nuclear receptors in nonalcoholic fatty liver disease

JA López-Velázquez, LD Carrillo-Córdova… - Journal of …, 2012 - Wiley Online Library
Nuclear receptors comprise a superfamily of ligand‐activated transcription factors that are
involved in important aspects of hepatic physiology and pathophysiology. There are about …

Emerging role of cellular cholesterol in the pathogenesis of nonalcoholic fatty liver disease

A Bashiri, G Tavallaee, L Li, DS Ng - Current opinion in lipidology, 2013 - journals.lww.com
Nonalcoholic fatty liver disease (NAFLD) is a highly prevalent disorder with the hallmark
being excess accumulation of hepatic triglycerides. It encompasses a wide spectrum of liver …

Nonalcoholic fatty liver disease: pathogenesis and potential for nuclear receptors as therapeutic targets

J George, C Liddle - Molecular Pharmaceutics, 2008 - ACS Publications
Nonalcoholic fatty liver disease (NAFLD) is a consequence of insulin resistance
encompassing a spectrum that extends from simple hepatic steatosis through to …