Treatment outcomes of molecular targeted therapy following nivolumab in metastatic renal cell carcinoma

Y Bando, J Furukawa, T Terakawa… - Japanese Journal of …, 2021 - academic.oup.com
Objective The purpose of this study was to assess the therapeutic efficacy of molecular
targeted therapies following nivolumab in metastatic renal cell carcinoma and to examine …

Assessment of prognostic factors in previously treated Japanese patients with metastatic renal cell carcinoma who received nivolumab: An observational multi‑institute …

T Ito, K Mizutani, K Takahara… - Molecular and …, 2022 - spandidos-publications.com
The aim of the present study was to evaluate the prognosis of Japanese patients with
metastatic renal cell carcinoma (mRCC) receiving nivolumab and to identify factors …

Efficacy of nivolumab versus molecular‐targeted therapy as second‐line therapy for metastatic renal cell carcinoma: Real‐world data from two Japanese institutions

H Ishihara, H Fukuda, T Takagi, T Kondo… - … Journal of Urology, 2021 - Wiley Online Library
Objectives To compare the efficacy of nivolumab with that of molecular‐targeted therapy as
a second‐line therapy for metastatic renal cell carcinoma using real‐world data. Methods …

Comparable efficacy and safety between second-line and later-line nivolumab therapy for metastatic renal cell carcinoma

H Ishihara, T Takagi, T Kondo, H Fukuda… - International Journal of …, 2020 - Springer
Background The aim of this study was to compare the efficacy and safety of nivolumab as
second-line and later-line (third-line or thereafter) therapy in metastatic renal cell carcinoma …

Rechallenge of nivolumab in metastatic renal cell carcinoma, an ambispective multicenter study (RENIVO).

C Vauchier, E Auclin, P Barthelemy, L Carril… - 2021 - ascopubs.org
330 Background: Immune checkpoint inhibitors (ICIs) in combination with another ICI or an
antiangiogenic targeted therapy have been approved for frontline therapy in metastatic renal …

A multicenter retrospective study of nivolumab monotherapy in previously treated metastatic renal cell carcinoma patients: interim analysis of Japanese real-world data

N Hinata, J Yonese, S Masui, Y Nakai… - International Journal of …, 2020 - Springer
Background In a phase III clinical trial, CheckMate 025, treatment of metastatic renal cell
carcinoma (mRCC) with nivolumab demonstrated superior efficacy over everolimus …

Nivolumab for metastatic renal cell carcinoma: results of a randomized phase II trial

RJ Motzer, BI Rini, DF McDermott… - Journal of clinical …, 2015 - ascopubs.org
Purpose Nivolumab is a fully human immunoglobulin G4 programmed death–1 immune
checkpoint inhibitor antibody that restores T-cell immune activity. This phase II trial assessed …

Effectiveness and safety of molecular-targeted therapy after nivolumab plus ipilimumab for advanced or metastatic renal cell carcinoma: a multicenter, retrospective …

K Iinuma, K Kameyama, T Taniguchi, K Kawada… - Cancers, 2022 - mdpi.com
Simple Summary We evaluated the efficacy and safety of molecular-targeted therapies
(MTTs) in 29 patients who discontinued the combination therapy of nivolumab plus …

Real-world effectiveness of nivolumab plus ipilimumab and second-line therapy in Japanese untreated patients with metastatic renal cell carcinoma: 2-year analysis …

T Kojima, R Kato, T Sazuka… - Japanese Journal of …, 2022 - academic.oup.com
Background Nivolumab plus ipilimumab combination therapy is one of the standard
therapies for untreated renal cell carcinoma patients with an International Metastatic Renal …

Site-specific response to nivolumab in renal cell carcinoma

T Negishi, N Furubayashi, T Nakagawa… - Anticancer …, 2021 - ar.iiarjournals.org
Background/Aim: Nivolumab monotherapy for advanced/metastatic renal cell carcinoma
(RCC) shows a survival benefit. The purpose of this study was to evaluate tumor responses …