Osteoporosis is characterized by systemic microarchitecture impairment and bone loss,
which ultimately lead to fragility fractures. This disease is most common in older people …

Objective To determine genome‐wide methylation profiles of bone from patients with hip
osteoarthritis (OA) and those with osteoporotic (OP) hip fractures. Methods Trabecular bone …

Osteoporosis is one of the most common age‐related progressive bone diseases in elderly
people. Approximately one in three women and one in five men are predisposed to …

Insufficient activity of the bone-forming osteoblasts leads to low bone mass and predisposes
to fragility fractures. The functional capacity of human mesenchymal stem cells (hMSCs), the …

ABSTRACT DNA methylation affects expression of associated genes and may contribute to
the missing genetic effects from genome-wide association studies of osteoporosis. To …

Osteoporosis is one of the most common metabolic skeletal diseases, which affects more
than 200 million people worldwide, especially elderly and postmenopausal women. One of …

Altered DNA methylation upon ageing may result in many age‐related diseases such as
osteoporosis. However, the changes in DNA methylation that occur in cortical bones, the …

DNA methylation is an important epigenetic modification that contributes to the lineage
commitment and specific functions of different cell types. In this study, we compared …

The aim of this study was to investigate the relationship between osteoporosis and
osteoarthritis by analyzing the DNA methylation in osteoporosis and osteoarthritis. The …

DNA methylation is one of the most studied epigenetic mechanisms that play a pivotal role in
regulating gene expression. The epigenetic component is strongly involved in aging-bone …