MicroRNAs and the heart: small things do matter

N Papoutsidakis, S Deftereos, A Kaoukis… - Current Topics in …, 2013 - ingentaconnect.com
MicroRNAs are small RNA molecules and constitute a relatively novel class of gene
expression regulators, found in the great majority of eukaryotic cells. Their role in human …

MicroRNAs and cardiovascular diseases

K Ono - MicroRNAs in Medicine, 2013 - Wiley Online Library
Recent gain‐and loss‐of‐function studies using in vitro and in vivo models have revealed
distinct roles for specific miRNAs in cardiovascular development, physiological functions …

Identification of microRNA–mRNA dysregulations in paroxysmal atrial fibrillation

DY Chiang, M Zhang, N Voigt, KM Alsina… - International Journal of …, 2015 - Elsevier
Background The molecular mechanisms underlying the early development of atrial
fibrillation (AF) remain poorly understood. Emerging evidence suggests that abnormal …

Introduction to the series on microRNAs in the cardiovascular system

E van Rooij - Circulation research, 2012 - Am Heart Assoc
Until recently, microRNAs (miRNAs) were considered to be relatively small players in
biological systems by having a balancing function through moderate effects on gene …

[HTML][HTML] Overview of microRNAs in cardiac hypertrophy, fibrosis, and apoptosis

J Wang, OW Liew, AM Richards, YT Chen - International journal of …, 2016 - mdpi.com
MicroRNAs (miRNAs) are non-coding RNAs that play essential roles in modulating the gene
expression in almost all biological events. In the past decade, the involvement of miRNAs in …

MicroRNA− a new diagnostic tool in coronary artery disease and myocardial infarction

P Fic, K Kowalczuk, A Grabarska, A Stepulak - Advances in Hygiene and …, 2014 - phmd.pl
Coronary artery disease remain one of the leading causes of mortality in the world,
indicating the need for innovative therapies and diagnosis for heart disease. MicroRNAs …

MicroRNA-328 contributes to adverse electrical remodeling in atrial fibrillation

Y Lu, Y Zhang, N Wang, Z Pan, X Gao, F Zhang… - Circulation, 2010 - Am Heart Assoc
Background—A characteristic of both clinical and experimental atrial fibrillation (AF) is atrial
electric remodeling associated with profound reduction of L-type Ca2+ current and …

Influence of atrial fibrillation on microRNA expression profiles in left and right atria from patients with valvular heart disease

N Cooley, MJ Cowley, RCY Lin… - Physiological …, 2012 - journals.physiology.org
Chronic atrial fibrillation (AF) is a complication associated with the dilated atria of patients
with valvular heart disease and contributes to worsened pathology. We examined microRNA …

The role of microRNA in the development, diagnosis, and treatment of cardiovascular disease: recent developments

A Wronska - Journal of Pharmacology and Experimental …, 2023 - ASPET
Since their discovery in 1993, microRNAs (miRNAs) have emerged as important regulators
of many crucial cellular processes, and their dysregulation have been shown to contribute to …

[HTML][HTML] Micrornas and cardiovascular diseases: from bench to bedside

R De Rosa, MV Polito, R Benvenga… - Translational …, 2017 - ncbi.nlm.nih.gov
MicroRNAs (microRNAs or miRs) are small, non-coding RNAs that control gene expression
by binding to and repressing specific mRNA target and have emered as powerful regulators …