Objective.—To review limitations of the use of serum anion gap in clinical practice. Data
Sources.—Original reports and reviews. Study Selection.—Sources containing the most …

We report the incidence of normal (50.4%), increased (46.7%), and decreased (2.9%) anion
gap among hospitalized patients in a retrospective study. The mean and range of increased …

• Using modern electrode technology (Beckman ASTRA analyzer), we evaluated the
reference range for the anion gap (calculated as sodium minus chloride minus bicarbonate …

The serum anion gap has been utilized to identify errors in the measurement of electrolytes,
to detect paraproteins, and, most relevant to the nephrologist, to evaluate patients with …

Because the anion gap is useful in classifying acid-base disorders, quantitative information
on this variable should be readily available. Three populations were studied and means and …

Background The purpose of this review is to provide a differential diagnosis for a low anion
gap. Methods We describe the anatomy of the anion gap. Also, we follow-up with a review of …

The anion gap can be readily calculated from routine laboratory data, and although it has its
widest application in the diagnosis of various forms of metabolic acidosis, 1, 2 it may …

Background: Conflicting data exist as to what extent hypoalbuminemia reduces the anion
gap; estimates range from 1.5 to 2.5 mM per g/dL decrease in serum albumin. Methods: We …

The anion gap (AG) in the serum equals the concentrations of Na-(Cl+ HCO3). It is
becoming increasingly useful in the interpretation of acid-base disorders and in the …

The serum anion gap, calculated from the electrolytes measured in the chemical laboratory,
is defined as the sum of serum chloride and bicarbonate concentrations subtracted from the …