Host membranes as drivers of virus evolution

M Matveeva, M Lefebvre, H Chahinian, N Yahi… - Viruses, 2023 - mdpi.com
The molecular mechanisms controlling the adaptation of viruses to host cells are generally
poorly documented. An essential issue to resolve is whether host membranes, and …

Convergent evolution dynamics of SARS-CoV-2 and HIV surface envelope glycoproteins driven by host cell surface receptors and lipid rafts: lessons for the future

J Fantini, H Chahinian, N Yahi - International journal of molecular …, 2023 - mdpi.com
Although very different, in terms of their genomic organization, their enzymatic proteins, and
their structural proteins, HIV and SARS-CoV-2 have an extraordinary evolutionary potential …

Electrostatic surface potential as a key parameter in virus transmission and evolution: how to manage future virus pandemics in the post-COVID-19 era

J Fantini, F Azzaz, H Chahinian, N Yahi - Viruses, 2023 - mdpi.com
Virus-cell interactions involve fundamental parameters that need to be considered in
strategies implemented to control viral outbreaks. Among these, the surface electrostatic …

Targeting lipid rafts as a strategy against coronavirus

M Sorice, R Misasi, G Riitano, V Manganelli… - Frontiers in Cell and …, 2021 - frontiersin.org
Lipid rafts are functional membrane microdomains containing sphingolipids, including
gangliosides, and cholesterol. These regions are characterized by highly ordered and tightly …

Lipid rafts as viral entry routes and immune platforms: A double-edged sword in SARS-CoV-2 infection?

R Roncato, J Angelini, A Pani, R Talotta - Biochimica et Biophysica Acta …, 2022 - Elsevier
Lipid rafts are nanoscopic compartments of cell membranes that serve a variety of biological
functions. They play a crucial role in viral infections, as enveloped viruses such as severe …

Viral modulation of lipid rafts and their potential as putative antiviral targets

YJ Gee, YL Sea, SK Lal - Reviews in Medical Virology, 2023 - Wiley Online Library
Lipid rafts are ubiquitous in cells. They are identified as cholesterol and glycosphingolipid
enriched microdomains on cellular membranes. They serve as platforms for cellular …

Membrane rafts: portals for viral entry

I Ripa, S Andreu, JA López-Guerrero… - Frontiers in …, 2021 - frontiersin.org
Membrane rafts are dynamic, small (10–200 nm) domains enriched with cholesterol and
sphingolipids that compartmentalize cellular processes. Rafts participate in roles essential to …

Coronavirus interplay with lipid rafts and autophagy unveils promising therapeutic targets

K Fecchi, S Anticoli, D Peruzzu, E Iessi… - Frontiers in …, 2020 - frontiersin.org
Coronaviruses are enveloped, single-stranded, positive-sense RNA viruses that can infect
animal and human hosts. The infection induces mild or sometimes severe acute respiratory …

Lipid droplet motility increases following viral immune stimulation

EA Monson, DR Whelan, KJ Helbig - International Journal of Molecular …, 2021 - mdpi.com
Lipid droplets (LDs) have traditionally been thought of as solely lipid storage compartments
for cells; however, in the last decade, they have emerged as critical organelles in health and …

Virus infection and lipid rafts

T Suzuki, Y Suzuki - Biological and Pharmaceutical Bulletin, 2006 - jstage.jst.go.jp
Virus entry, assembly, and budding are important processes in the replication cycle of a
virus. Viruses are dependent on host living cells for their replication. Viruses use the …