Human epididymis protein 4, a novel potential biomarker for diagnostic and prognosis monitoring of lung cancer

T Zhang, L Chu, W Tan, C Ye… - The Clinical Respiratory …, 2024 - Wiley Online Library
Objective This study aimed to explore the application value of human epididymis protein 4
(HE4) in diagnosing and monitoring the prognosis of lung cancer. Methods First, TCGA (The …

[HTML][HTML] Clinical usefulness of human epididymis protein 4 in lung cancer

SI Choi, MA Jang, BR Jeon, HB Shin… - Annals of Laboratory …, 2017 - ncbi.nlm.nih.gov
Abstract Human epididymis protein 4 (HE4) has been suggested as a useful new biomarker
of lung cancer; however, few relevant large-scale studies have been published. In this study …

[HTML][HTML] Human epididymis protein 4 may not be a reliable screening biomarker for detecting lung carcinoma patients

B Celik, T Bulut - Biomedical Reports, 2017 - spandidos-publications.com
Abstract Human epididymis protein 4 (HE4) acts as a protease inhibitor. It has been detected
in the serum of patients with lung cancer patients and its utility for lung cancer screening was …

Serum human epididymis protein 4 (HE4) may be a better tumor marker in early lung cancer

Q Zeng, M Liu, N Zhou, L Liu, X Song - Clinica Chimica Acta, 2016 - Elsevier
Background Human epididymis protein 4 (HE4) had been shown to be an ideal biomarker in
ovarian cancer. However, there were fewer reports on its application in lung cancer. We …

Serum HE4 as a diagnostic and prognostic marker for lung cancer

K Iwahori, H Suzuki, Y Kishi, Y Fujii, R Uehara… - Tumor Biology, 2012 - Springer
We evaluated the diagnostic and prognostic efficacy of human epididymis protein 4 (HE4)
for lung cancer patients by using our novel enzyme-linked immunosorbent assay (ELISA) …

Serum human epididymis protein 4 (HE4) as a tumor marker in men with lung cancer

B Nagy Jr, HP Bhattoa, Z Steiber, M Csobán… - Clinical Chemistry and …, 2014 - degruyter.com
Background: Human epididymis protein 4 (HE4) is a reliable tumor marker for ovarian
cancer, but only limited data are available on HE4 levels in lung malignancies. Methods …

Diagnostic value of human epididymis protein 4 in malignant pleural effusion in lung cancer

M Lv, F Wang, X Wang, C Zhang - Cancer Biomarkers, 2019 - content.iospress.com
OBJECTIVE: This study aimed to assess the diagnostic value of human epididymis protein 4
(HE4) in the pleural effusion of lung cancer patients. METHODS: HE4 protein in the pleural …

Evaluating the expression and diagnostic value of human epididymis protein 4 (HE4) in small cell lung cancer

X Wang, Y Fan, J Wang, H Wang, W Liu - Tumor Biology, 2014 - Springer
We evaluated the expression and diagnostic value of human epididymis protein 4 (HE4) in
small cell lung cancer (SCLC). Serum HE4 level was measured in serum samples from 30 …

Serum level of HE4 is closely associated with pulmonary adenocarcinoma progression

S Yamashita, K Tokuishi, T Moroga, S Yamamoto… - Tumor Biology, 2012 - Springer
Abstract The human epididymis 4 (HE4) protein is expressed in the epididymis and
respiratory tract. We previously reported that HE4 is also expressed in pulmonary …

[HTML][HTML] Expression level of serum human epididymis 4 and its prognostic significance in human non-small cell lung cancer

Y Jiang, C Wang, B Lv, G Ma… - International Journal of …, 2014 - ncbi.nlm.nih.gov
The prognostic significance of serum human epididymis protein 4 (HE4) levels in human
NSCLC among a Chinese population has not been investigated. The purpose of this study …