[HTML][HTML] Bone and ocular safety of budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler in COPD: a 52-week randomized study

EM Kerwin, GT Ferguson, M Mo, K DeAngelis… - Respiratory …, 2019 - Springer
Background Long-term use of inhaled corticosteroids (ICSs) has been associated with
increased risk of bone and ocular comorbidities. We evaluated the effects of the triple fixed …

[HTML][HTML] A randomized, double-blind, double-dummy study of glycopyrrolate/formoterol fumarate metered dose inhaler relative to umeclidinium/vilanterol dry powder …

F Maltais, GT Ferguson, GJ Feldman, G Deslee… - Advances in …, 2019 - Springer
Introduction Glycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI), formulated
using co-suspension delivery technology, is the only approved fixed-dose combination long …

One year prospective open study of the effect of high dose inhaled steroids, fluticasone propionate, and budesonide on bone markers and bone mineral density

JA Hughes, BG Conry, SM Male, R Eastell - Thorax, 1999 - thorax.bmj.com
BACKGROUND Inhaled corticosteroids are recognised as the most effective agents in the
treatment of asthma. However, concerns have been expressed about the effects of high …

Long-term use of inhaled glucocorticoids in patients with stable chronic obstructive pulmonary disease and risk of bone fractures: a narrative review of the literature

G Caramori, P Ruggeri, F Arpinelli, L Salvi… - International journal of …, 2019 - Taylor & Francis
Patients with chronic obstructive pulmonary disease (COPD) demonstrate a greater
osteoporosis prevalence than the general population. This osteoporosis risk may be …

[HTML][HTML] Inhaled corticosteroids effects on bone in asthmatic and COPD patients: a quantitative systematic review

F Richy, J Bousquet, GE Ehrlich, PJ Meunier… - Osteoporosis …, 2003 - Springer
Deleterious effect of oral corticosteroids on bone has been well documented, whereas this
remains debated for inhaled ones (ICS). Our objectives were to analyze the effects of ICS on …

Clinical Safety of Long-Acting β2-Agonist and Inhaled Corticosteroid Combination Therapy in COPD

M Decramer, G Ferguson - COPD: Journal of Chronic Obstructive …, 2006 - Taylor & Francis
Long-acting β 2-agonist (LABA) and inhaled corticosteroid (ICS) combination therapy is
recommended by international treatment guidelines for COPD. The current literature …

Prevalence and progression of osteoporosis in patients with COPD: results from the TOwards a Revolution in COPD Health study

GT Ferguson, PMA Calverley, JA Anderson… - Chest, 2009 - Elsevier
Background Osteoporosis is common in patients with COPD, but its prevalence and
progression are not well characterized. Concerns have been raised over the possible …

Do inhaled steroids reduce bone mineral density and increase fracture risk?

C Wheelock, J Glass, L St Anna - 2012 - mospace.umsystem.edu
Inhaled corticosteroids (ICS) at low to medium doses (< 1500 mcg beclomethasone
hydrofluoroalkane per day) for asthma and chronic obstructive pulmonary disease (COPD) …

Inhaled corticosteroids in the long-term management of patients with chronic obstructive pulmonary disease

DD Sin, SFP Man - Drugs & aging, 2003 - Springer
Chronic obstructive pulmonary disease (COPD) is a major problem in the elderly population,
with approximately 10% of the population affected. Since COPD is an inflammatory disorder …

Effect of once-daily fluticasone furoate/vilanterol versus vilanterol alone on bone mineral density in patients with COPD: a randomized, controlled trial

F Maltais, I Schenkenberger… - Therapeutic …, 2020 - journals.sagepub.com
Background: The relationship between inhaled corticosteroids and bone mineral density
(BMD) remains uncertain despite extensive research. Methods: This was an international …