Continuum models of membrane fusion: Evolution of the theory

SA Akimov, RJ Molotkovsky, PI Kuzmin… - International journal of …, 2020 - mdpi.com
Starting from fertilization, through tissue growth, hormone secretion, synaptic transmission,
and sometimes morbid events of carcinogenesis and viral infections, membrane fusion …

Control of membrane fusion mechanism by lipid composition: predictions from ensemble molecular dynamics

PM Kasson, VS Pande - PLoS computational biology, 2007 - journals.plos.org
Membrane fusion is critical to biological processes such as viral infection, endocrine
hormone secretion, and neurotransmission, yet the precise mechanistic details of the fusion …

Stalk model of membrane fusion: solution of energy crisis

Y Kozlovsky, MM Kozlov - Biophysical journal, 2002 - cell.com
Membrane fusion proceeds via formation of intermediate nonbilayer structures. The stalk
model of fusion intermediate is commonly recognized to account for the major …

Model systems for membrane fusion

HR Marsden, I Tomatsu, A Kros - Chemical Society Reviews, 2011 - pubs.rsc.org
Membrane fusion has an overarching influence on living organisms. The fusion of sperm
and egg membranes initiates the life of a sexually reproducing organism. Intracellular …

The computational route from bilayer membranes to vesicle fusion

JC Shillcock, R Lipowsky - Journal of Physics: Condensed Matter, 2006 - iopscience.iop.org
Biological membranes are examples of'smart'materials whose properties and behaviour
emerge from the propagation across many scales of the molecular characteristics of their …

New mechanism of membrane fusion

M Müller, K Katsov, M Schick - The Journal of Chemical Physics, 2002 - pubs.aip.org
Fusion of membranes is involved in basic biological processes but its mechanism remains
poorly understood. That different proteins trigger different fusion events obscures the …

Intermediates and kinetics of membrane fusion

J Bentz - Biophysical journal, 1992 - cell.com
Recently, it has become clear that the influenza virus fusion protein, hemagglutinin (HA),
produces membrane destabilization and fusion by a multistep process, which involves the …

Lipid acrobatics in the membrane fusion arena

AJ Markvoort, SJ Marrink - Current Topics in Membranes, 2011 - Elsevier
Publisher Summary This chapter describes the recent contribution of computer simulation
approaches to unravel the molecular details of membrane fusion. Over the past decade …

Membrane fusion

R Jahn, H Grubmüller - Current opinion in cell biology, 2002 - Elsevier
Fusion of biological membranes is governed by physical principles but it is unclear whether
the transition states are primarily determined by lipid physics or by protein–lipid interactions …

Mechanics of membrane fusion

LV Chernomordik, MM Kozlov - Nature structural & molecular biology, 2008 - nature.com
Diverse membrane fusion reactions in biology involve close contact between two lipid
bilayers, followed by the local distortion of the individual bilayers and reformation into a …