Arylacetamide deacetylase (AADAC), a microsomal serine esterase, hydrolyzes drugs, such
as flutamide, phenacetin and rifampicin. Because AADAC has not been fully investigated at …

Human arylacetamide deacetylase (AADAC) is a major esterase responsible for the
hydrolysis of clinical drugs such as flutamide, phenacetin, and rifampicin. Thus, AADAC is …

Human arylacetamide deacetylase (AADAC) is responsible for the hydrolysis of clinically
used drugs such as flutamide, phenacetin, and rifamycins. Our recent studies suggested that …

Human arylacetamide deacetylase (AADAC) is a single microsomal serine esterase
involved in the hydrolysis of many acetyl-containing drugs. To date, the presence and …

Human arylacetamide deacetylase (AADAC) is an esterase responsible for the hydrolysis of
some drugs, including flutamide, indiplon, phenacetin, and rifamycins. AADAC is highly …

Human arylacetamide deacetylase (AADAC) can hydrolyze clinical drugs such as flutamide,
phenacetin, and rifamycins. AADAC is a glycoprotein, but the role of glycosylation remains …

Human arylacetamide deacetylase (AADAC) catalyzes the hydrolysis of some clinically used
drugs, but the information available on its substrates is limited. To increase our knowledge of …

Background Arylacetamide deacetylase (AADAC) is a lipolytic enzyme involved in
xenobiotic metabolism. The characterization in terms of activity and substrate preference has …

Carboxylesterase (CES) and arylacetamide deacetylase (AADAC) are the major enzymes
responsible for the hydrolysis of various clinical drugs. Our recent study demonstrated that …

Human arylacetamide deacetylase (AADAC) plays a role in the detoxification or activation of
drugs and is sometimes involved in the incidence of toxicity by catalyzing hydrolysis …