Pharmacological importance of TG12 from tachykinin and its toxicological behavior against multidrug-resistant bacteria Klebsiella pneumonia

SV Raju, P Sarkar, M Pasupuleti, NT Saraswathi… - … and Physiology Part C …, 2021 - Elsevier
Abstract Development of antimicrobial drugs against multidrug-resistant (MDR) bacteria is a
great focus in recent years. TG12, a short peptide molecule used in this study was screened …

Antibacterial Activity of RM12, a Tachykinin Derivative, Against Pseudomonas aeruginosa

SV Raju, P Sarkar, M Pasupuleti, AM Abbasi… - International Journal of …, 2021 - Springer
Bacterial infections are increasing in recent years and developing with more resistance to
antibiotics. There is a need of designing antimicrobial peptides (AMP) against these …

Novel hybrid peptide cathelicidin 2 (1-13)-thymopentin (TP5) and its derived peptides with effective antibacterial, antibiofilm, and anti-adhesion activities

HN Guo, YC Tong, HL Wang, J Zhang, ZX Li… - International journal of …, 2021 - mdpi.com
The increasing numbers of infections caused by multidrug-resistant (MDR) pathogens
highlight the urgent need for new alternatives to conventional antibiotics. Antimicrobial …

Identification of a Novel Antimicrobial Peptide From the Ancient Marine Arthropod Chinese Horseshoe Crab, Tachypleus tridentatus

WF Wang, XY Xie, Y Huang, YK Li, H Liu… - Frontiers in …, 2022 - frontiersin.org
Humoral immunity is the first line of defense in the invertebrate immune system, and
antimicrobial peptides play an important role in this biological process. A novel antimicrobial …

Genome-Wide Identification of Trachinotus ovatus Antimicrobial Peptides and Their Immune Response against Two Pathogen Challenges

Y Liang, JM Pan, KC Zhu, L Xian, HY Guo, BS Liu… - Marine Drugs, 2023 - mdpi.com
Golden pompano, Trachinotus ovatus, as a highly nutritious commercially valuable marine
fish, has become one of the preferred species for many fish farmers due to its rapid growth …

Two Tachykinin-Related Peptides with Antimicrobial Activity Isolated from Triatoma infestans Hemolymph

LCL Diniz, FL Alves, A Miranda… - Microbiology …, 2020 - journals.sagepub.com
Antimicrobial peptides and proteins (AMPs) are molecules that can interact with microbial
cells and lead to membrane disruption or intracellular molecule interactions and death …

6His-tatritin promotes antimicrobial defense via regulating immune ability and intestinal microbial community in grass carp (Ctenopharyngodon idella)

WF Wang, CX Cheng, H Liu, XL Chen… - Fish & Shellfish …, 2023 - Elsevier
Antimicrobial peptides are small, cationic, and amphiphilic peptides found in most
organisms, and many of these peptides have broad antimicrobial activity against Gram …

Antimicrobial properties of hemokinin-1 against strains of Pseudomonas aeruginosa

A Berger, AH Tran, H Dedier, MA Gardam, CJ Paige - Life sciences, 2009 - Elsevier
AIMS: In this study, we examined whether hemokinin-1, the newest member of the tachykinin
family and a close relative of substance P, has antimicrobial properties which have been …

Microbial synthesis of three metabolites of a tachykinin receptor antagonist, TAK-637

N Tarui, Y Ikeura, H Natsugari, K Nakahama - Journal of bioscience and …, 2001 - Elsevier
The compound TAK-637 ((aR, 9R)-7-[3, 5-bis (trifluoromethyl) benzyl]-8, 9, 10, 11-tetrahydro-
9-methyl-5-(4-methylphenyl)-7H-[1, 4] diazocino [2, 1-g][1, 7] naphthyridine-6, 13-dione), a …

[HTML][HTML] Characterization and functional analysis of three novel liver-expressed antimicrobial peptide 2 (LEAP-2) in Glyptothorax zanaensis

S Cai, P Liu, S Liu, X Cao, J Peng, K Meng, Y Qu - Aquaculture Reports, 2023 - Elsevier
Liver-expressed antimicrobial peptide 2 (LEAP-2) is an important component of innate
immunity, a well-conserved, evolutionarily ancient host defensive mechanism. In this study …