Cathelicidin-DM is an Antimicrobial Peptide from Duttaphrynus melanostictus and Has Wound-Healing Therapeutic Potential

Y Shi, C Li, M Wang, Z Chen, Y Luo, X Xia, Y Song… - ACS …, 2020 - ACS Publications
Antimicrobial peptides (AMPs) are a class of templates with application potential for drug
development. Amphibians are important sources of AMPs. Duttaphrynus melanostictus is the …

Identification and Design of Novel Potential Antimicrobial Peptides Targeting Mycobacterial Protein Kinase PknB

H Deka, A Pawar, M Battula, AA Ghfar, ME Assal… - The Protein …, 2024 - Springer
Antimicrobial peptides have gradually gained advantages over small molecule inhibitors for
their multifunctional effects, synthesising accessibility and target specificity. The current …

JcTI-PepI, a synthetic peptide bioinspired in the trypsin inhibitor from Jatropha curcas, presents potent inhibitory activity against C. krusei, a neglected pathogen

LAL Souza, LP Dias, NMS Araújo, RF Carneiro… - Biochimie, 2022 - Elsevier
Antimicrobial resistance has been increasing globally, posing a global public health risk. It
has prompted the scientific community to look for alternatives to traditional drugs …

Bactericidal efficiency and modes of action of the novel antimicrobial peptide T9W against Pseudomonas aeruginosa

X Zhu, A Shan, Z Ma, W Xu, J Wang… - Antimicrobial agents …, 2015 - Am Soc Microbiol
The antipseudomonal efficiency and mechanism of action of a novel engineered
antimicrobial peptide, T9W, were evaluated in this study. T9W displayed high activity, with a …

Antimicrobial and anti-inflammatory activities of short dodecapeptides derived from duck cathelicidin: Plausible mechanism of bactericidal action and endotoxin …

SD Kumar, SY Shin - European journal of medicinal chemistry, 2020 - Elsevier
Antimicrobial peptides (AMPs) have gained increasing attention to combat antibiotic-
resistant pathogens. dCATH (duck cathelicidin) is a 20-residue avian cathelicidin with potent …

Anticancer activities of antimicrobial BmKn2 peptides against oral and colon cancer cells

T Arpornsuwan, W Sriwai, J Jaresitthikunchai… - International journal of …, 2014 - Springer
There is considerable current interest in developing antimicrobial and anticancer agents
with a new mode of action. The antimicrobial peptides are regarded as a potential solution …

Innate immune function of serine/threonine-protein kinase from Macrobrachium rosenbergii in response to host-pathogen interactions

G Ravichandran, M Pasupuleti, MV Arasu… - Fish & Shellfish …, 2020 - Elsevier
The occurrences of multiple drug-resistant strains have been relentlessly increasing in
recent years. The aquaculture industry has encountered major disease outbreaks and …

Studies on the antibacterial activity and mechanism of antimicrobial peptides against drug-resistant bacteria

X Luo, Y Liu, Z Qin, Z Jin, L Xu, Y Liu… - Journal of …, 2018 - ingentaconnect.com
Antibiotic resistance is a growing threat to human health. More than anything else, multidrug-
resistant gram-negative bacteria pose the biggest challenge to healthcare, which is …

[PDF][PDF] The protein profiling of asian giant toad skin secretions and their antimicrobial activity

SS Dahham, CS Hew, I Jaafar… - International Journal of …, 2016 - researchgate.net
Objective: The skin secretions of toads are a rich source of bioactive peptides and proteins,
which offer a wide range of therapeutic application. The current study was designed to …

Exploring the Role of Cathelicidin Antimicrobial Peptide, Toll-Like Receptor 4, and HMGB-1 in Bacterial Infection

A Febriza, HH Idrus, VN Kasim - Anti-Infective Agents, 2024 - ingentaconnect.com
Background and Aim: Lipopolysaccharides (LPS) from Salmonella typhi will attach with Toll-
Like Receptor 4 (TLR-4) and trigger an inflammatory response to fight the pathogen. Due to …