TC26, a teleost TFPI-1 derived antibacterial peptide that induces degradation of bacterial nucleic acids and inhibits bacterial infection in vivo

Y Su, G Wang, J Wang, B Xie, Q Gu, D Hao… - Fish & shellfish …, 2020 - Elsevier
At present, several reports have indicated that the C-terminal peptides of tissue factor
pathway inhibitor 1 (TFPI-1) were active antibacterial peptides. However, the functions of …

Design of a Sea snake antimicrobial peptide derivative with therapeutic potential against drug-resistant bacterial infection

J Gao, M Zhang, F Zhang, Y Wang… - ACS Infectious …, 2020 - ACS Publications
Infections caused by drug-resistant pathogens are a worldwide challenge for public health.
Antimicrobial peptides (AMPs) are regarded as promising antibiotic alternatives for the …

In vitro immunomodulatory activities of peptides derived from Salmo salar NK-lysin and cathelicidin in fish cells

J Acosta, F Roa, I González-Chavarría, A Astuya… - Fish & shellfish …, 2019 - Elsevier
Antimicrobial peptides (AMPs) are amphipathic peptides, which play an important role in
innate defence. These peptides are gene-encoded and either constitutively expressed …

[HTML][HTML] Transcriptome profiling and in silico detection of the antimicrobial peptides of red king crab Paralithodes camtschaticus

IA Yakovlev, E Lysøe, I Heldal, H Steen, SB Hagen… - Scientific Reports, 2020 - nature.com
Endogenous antimicrobial peptides (AMPs) are evolutionarily ancient factors of innate
immunity, which are produced by all multicellular organisms and play a key role in their …

Cloning and functional characterization of a new antimicrobial peptide gene StCT1 from the venom of the scorpion Scorpiops tibetanus

W Yuan, L Cao, Y Ma, P Mao, W Wang, R Zhao, Y Wu… - Peptides, 2010 - Elsevier
Scorpion has an innovative venom gland, which is an important determinant in contributing
to its successful survival for more than 400 million years. Scorpion venom contains a …

Characterization of Purified Tachystatin-A2 Isolated from Amoebocytes of Asian Horseshoe Crab, Tachypleus gigas as Potential Antibacterial Peptide

MMM Kasturi, NA Kamaruding, N Ismail - Applied Biochemistry and …, 2021 - Springer
Nowadays, an alarming increase in antibiotics resistance have steered intensive research to
explore new substitutes for ineffective antibiotics. This study aimed (1) to identify the purified …

NKHs27, a sevenband grouper NK-Lysin peptide that possesses immunoregulatory and antimicrobial activity

C Wang, X Yan, G Wang, W Liu, Y Wang, D Hao… - Fish & Shellfish …, 2023 - Elsevier
As an effective and broad-spectrum antimicrobial peptide, NK-Lysin is attracted more and
more attention at present. However, the functions and action mechanism of NK-Lysin …

Transcriptome Analysis Reveals the Resistance Mechanism of Pseudomonas aeruginosa to Tachyplesin I

J Hong, H Jiang, J Hu, L Wang, R Liu - Infection and Drug …, 2020 - Taylor & Francis
Background: Tachyplesin I is a cationic antimicrobial peptide with a typical cyclic antiparallel
β-sheet structure. We previously demonstrated that long-term continuous exposure to …

[HTML][HTML] Cell specificity, anti-inflammatory activity, and plausible bactericidal mechanism of designed Trp-rich model antimicrobial peptides

KH Park, YH Nan, Y Park, JI Kim, IS Park… - … et Biophysica Acta (BBA …, 2009 - Elsevier
To develop novel short Trp-rich antimicrobial peptides (AMPs) with potent cell specificity
(targeting bacteria but not eukaryotic cells) and anti-inflammatory activity, a series of 11 …

Effect of dimerization of a β-turn antimicrobial peptide, PST13-RK, on antimicrobial activity and mammalian cell toxicity

ST Yang, JI Kim, SY Shin - Biotechnology letters, 2009 - Springer
Abstract PST13-RK (KKKFPWWWPFKKK-NH 2) is an improved derivative of tritrpticin
adopting a β-turn structure. In order to investigate the effect of dimerization of PST13-RK on …