Can calcitonin gene-related peptide (CGRP) and pentraxin-3 (PTX-3) be useful in diagnosing acute migraine attack?

S Vural, L Albayrak - Journal of Receptors and Signal Transduction, 2022 - Taylor & Francis
Purpose Even if migraine is not fatal, it is a common and challenging disease with adverse
effects on individuals' lives. The lack of objective diagnostic tools causes delays in diagnosis …

Feasibility of serum CGRP measurement as a biomarker of chronic migraine: a critical reappraisal

MJ Lee, SY Lee, S Cho, ES Kang… - The journal of headache …, 2018 - Springer
Background Calcitonin gene-related peptide (CGRP) has been reported as elevated in
chronic migraine. We aimed to validate the role of interictal serum CGRP concentration in …

Calcitonin gene-related peptide as a biomarker in migraine

AI Alemam, WM Alsheikh, IA Alahmar - Journal of Neurology Research, 2018 - neurores.org
Background: Migraine is a prevalent disease with much economic burden and relatively
inadequate available treatment. Calcitonin gene-related peptide (CGRP) is the most …

Calcitonin gene-related peptide in peripheral blood as a biomarker for migraine

C Ramón, E Cernuda-Morollón… - Current Opinion in …, 2017 - journals.lww.com
Although CGRP data must be confirmed and expanded in future studies and specificity of
CGRP levels should be studied in entities able to resemble migraine, it seems that …

Association of serum levels of calcitonin gene-related peptide and cytokines during migraine attacks

D Han - Annals of Indian Academy of Neurology, 2019 - journals.lww.com
Background: During a migraine attack, trigeminal activation results in the release of
calcitonin gene-related peptide (CGRP), which stimulates the release of inflammatory …

Plasma calcitonin gene-related peptide concentration is comparable to control group among migraineurs and tension type headache subjects during inter-ictal period

R Gupta, T Ahmed, B Banerjee, M Bhatia - The journal of headache and …, 2009 - Springer
Calcitonin gene-related peptide (CGRP) is known to increase during acute attack of
migraine and tension type headache (TTH). However, its concentration during inter-ictal …

Serum levels of pentraxin-3 and other inflammatory biomarkers in migraine: association with migraine characteristics

M Ceylan, OF Bayraktutan, S Becel, Ö Atis… - …, 2016 - journals.sagepub.com
Background Several studies have been conducted on the inflammatory aspects of migraine.
Pentraxins are a novel and important part of innate immunity as a superfamily of acute …

Is calcitonin gene-related peptide a reliable biochemical marker of migraine?

B Tesfay, WK Karlsson, RD Moreno… - Current opinion in …, 2022 - journals.lww.com
Current evidence does not justify the usage of CGRP levels as a biomarker for diagnosing
migraine or for determining the severity of the disease in individual patients. However …

Pentraxin 3 level in acute migraine attack with aura: Patient management in the emergency department

MT Gokdemir, C Nas, GS Gokdemir - The American Journal of Emergency …, 2020 - Elsevier
Objectives We investigated the state of inflammation, PTX3 level and other routine
inflammatory markers (high sensitivity C-reactive protein [hsCRP], and white blood cells …

Untangling the mess of CGRP levels as a migraine biomarker: an in-depth literature review and analysis of our experimental experience

G Gárate, J Pascual, M Pascual-Mato, J Madera… - The Journal of …, 2024 - Springer
Background Calcitonin gene-related peptide (CGRP) is the most promising candidate to
become the first migraine biomarker. However, literature shows clashing results and …