A new era for migraine: the role of calcitonin gene-related peptide in the trigeminovascular system

ST Chen, JW Wu - Progress in Brain Research, 2020 - Elsevier
There is a huge improvement in our understanding of migraine pathophysiology in the past
decades. The activation of the trigeminovascular system has been proved to play a key role …

[HTML][HTML] Serum calcitonin gene-related peptide in patients with persistent post-concussion symptoms, including headache: a cohort study

PP Eggertsen, J Palmfeldt, HW Schytz, D Hay… - Journal of …, 2024 - Springer
Background Calcitonin gene-related peptide (CGRP) plays an important role in migraine
pathophysiology, and post-traumatic headache (PTH) frequently presents with migraine-like …

Plasma calcitonin gene-related peptide in diagnosing and predicting paediatric migraine

PC Fan, PH Kuo, SH Chang, WT Lee, RM Wu… - …, 2009 - journals.sagepub.com
To investigate the role of plasma calcitonin gene-related peptide (CGRP) in paediatric
migraine, we prospectively collected 134 blood samples during or between attacks from 66 …

Calcitonin gene-related peptide in migraine: intersection of peripheral inflammation and central modulation

AC Raddant, AF Russo - Expert reviews in molecular medicine, 2011 - cambridge.org
Over the past two decades, a convergence of basic and clinical evidence has established
the neuropeptide calcitonin-gene-related peptide (CGRP) as a key player in migraine …

Serum CGRP, VIP, and PACAP usefulness in migraine: a case–control study in chronic migraine patients in real clinical practice

S Pérez-Pereda, M Toriello-Suárez… - Molecular Biology …, 2020 - Springer
Calcitonin gene-related peptide (CGRP), vasoactive intestinal peptide (VIP) and pituitary
adenylate cyclase activating polypetide-38 (PACAP-38) have relevant roles in migraine …

Evidence for increased plasma levels of calcitonin gene-related peptide in migraine outside of attacks

M Ashina, L Bendtsen, R Jensen, S Schifter, J Olesen - Pain, 2000 - journals.lww.com
Although calcitonin gene-related peptide (CGRP) has been shown to be elevated in jugular
venous blood of adult migraineurs during acute migraine attacks, it remains unknown …

Elevated saliva calcitonin gene‐related peptide levels during acute migraine predict therapeutic response to rizatriptan

RK Cady, CV Vause, TW Ho, ME Bigal… - … : The Journal of Head …, 2009 - Wiley Online Library
Objectives.—(1) To measure calcitonin gene‐related peptide (CGRP) levels in the saliva of
individuals with migraine during the premonitory period, mild headache, moderate to severe …

Calcitonin gene‐related peptide (CGRP) is a key molecule released in acute migraine attacks—Successful translation of basic science to clinical practice

L Edvinsson - Journal of Internal Medicine, 2022 - Wiley Online Library
Migraine is a highly prevalent neurovascular disorder afflicting more than 15% of the global
population. Nearly three times more females are afflicted by migraine in the 18–50 years …

Calcitonin gene-related peptide triggers migraine-like attacks in patients with migraine with aura

JM Hansen, AW Hauge, J Olesen, M Ashina - Cephalalgia, 2010 - journals.sagepub.com
Introduction: Calcitonin gene-related peptide (CGRP) is a key molecule in migraine
pathogenesis. Intravenous CGRP infusion triggers delayed migraine-like attacks in patients …

Calcitonin gene‐related peptide (CGRP) and migraine

PL Durham - Headache: The Journal of Head and Face Pain, 2006 - Wiley Online Library
The neuropeptide calcitonin gene‐related peptide (CGRP) has long been postulated to play
an integral role in the pathophysiology of migraine. While clinical findings are consistent with …