Abstract Aims Brugada syndrome (BrS) is associated with an increased risk of sudden
cardiac death due to ventricular tachycardia/fibrillation (VT/VF) in young, otherwise healthy …

Abstract The Brugada syndrome (BrS) is a rare heritable cardiac arrhythmia disorder
associated with ventricular fibrillation and sudden cardiac death. Mutations in the SCN5A …

For the last 10 years, applying new sequencing technologies to thousands of whole exomes
has revealed the high variability of the human genome. Extreme caution should thus be …

Brugada syndrome is an inherited arrhythmogenic disorder leading to sudden death
predominantly in the 3–4 decade. To date the only reliable treatment is the implantation of a …

Background: The genotype-phenotype correlation of SCN5A mutations as a predictor of
cardiac events in Brugada syndrome remains controversial. We aimed to establish a registry …

Brugada syndrome (BrS) is an inherited arrhythmogenic disease associated with sudden
cardiac death. The main gene is SCN5A. Additional variants in 42 other genes have been …

Objectives: We have tested whether a genotype-phenotype relationship exists in Brugada
syndrome (BS) by trying to distinguish BS patients with (carriers) and those without (non …

Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A
mutations in around 20% of cases,,. Through a genome-wide association study of 312 …

Brugada syndrome is a rare inherited arrhythmogenic disease leading to ventricular
fibrillation and high risk of sudden death. In 1998, this syndrome was linked with a genetic …

Brugada syndrome is a rare, inherited cardiac disease leading to ventricular fibrillation and
sudden cardiac death in structurally normal hearts. Clinical diagnosis requires a Brugada …