Pineal hormone melatonin is widely used in the treatment of disorders of circadian rhythms.
The presence of melatonin receptors in various animal tissues motivates the use of this …

This paper includes how melatonin and its related analogs interact with melatonin receptors
with the hope of developing important tools and agents of significant clinical and scientific …

Melatonin MT1 and MT2 receptor ligands have been vigorously explored for the last 4
decades. Inspection of approximately 80 publications in the field revealed that most …

Melatonin is a natural hormone primarily released by the pineal gland that regulates the
sleep-wake cycles. The diverse biological applications of melatonin, together with the need …

The goal of the article is to provide a clearer understanding of how melatonin and its related
analogs interact with melatonin receptors with the hope of developing important tools and …

In recent years, many physiological properties of melatonin have been described resulting in
much interest in the development of synthetic compounds possessing agonist or antagonist …

In humans, the hormone melatonin is produced and secreted from the pineal gland following
a circadian rhythm with high levels during the normal hours of sleep at night and low levels …

Importance of the field: Melatonin is a major chronobiological regulator involved in circadian
phasing, sleep, and numerous other functions including cyto-/neuroprotection, immune …

The search for melatonin receptor agonists formed the main part of melatonin medicinal
chemistry programs for the last three decades. In this short review, we summarize the two …

The pineal hormone melatonin has become the subject of considerable speculation in both
the scientific and lay press. Media coverage, coupled with scientific interest fuelled by the …