Insights into the Therapeutic Potential of Phytoconstituents as an Epigenetic Modulators in Diabetic Nephropathy

K Thapa, H Khan, AK Grewal, N Kanojia, G Kaur… - Current Pharmacology …, 2023 - Springer
Chronic diabetes is commonly associated with the development of nephropathy, which is a
prevalent complication. Hyperglycemia is believed to initiate various biochemical …

Bioactive phytochemicals that regulate the cellular processes involved in diabetic nephropathy

A Parveen, M Jin, SY Kim - Phytomedicine, 2018 - Elsevier
Background Owing to the multiple causative factors, the current advances in medication for
diabetic nephropathy (DN) do not appear to have improved therapies for patients …

To explore the putative molecular targets of diabetic nephropathy and their inhibition utilizing potential phytocompounds

B Bhattacharjee, A Chakrovorty… - Current Medicinal …, 2024 - ingentaconnect.com
Background: This review critically addresses the putative molecular targets of Diabetic
Nephropathy (DN) and screens effective phytocompounds that can be therapeutically …

Metabolic memory and diabetic nephropathy: Beneficial effects of natural epigenetic modifiers

K Kushwaha, S Sharma, J Gupta - Biochimie, 2020 - Elsevier
Nephropathy is one of the most frequent complications of chronic diabetes. The main reason
for nephropathy despite being hyperglycemia, but it progresses even after good glycemic …

[PDF][PDF] Therapeutic potential and epigenetic alterations of plant phytochemicals (as epi-drugs) for the treatment of type 2 diabetes mellitus: a systematic review

KK Kaur, G Allahbadia, M Singh - Adv. Obes. Weight Manag …, 2021 - researchgate.net
There has been a significant escalation of type2 diabetes mellitus (T2DM), all over the world
in particular more recently, secondary to population, age, obesity in addition to the sedentary …

Medicinal plants and diabetic kidney disease; an updated review on the recent findings

F Dehghan-Shahreza, SS Beladi-Mousavi… - Immunopathologia …, 2016 - immunopathol.com
In diabetes mellitus, hyperglycemia happens as a consequence of complex metabolic
disorders where immune, genetic, lifestyle and environmental factors cause an inadequate …

[HTML][HTML] Mechanisms of herbal nephroprotection in diabetes mellitus

D Dragoș, MM Manea, D Timofte… - Journal of Diabetes …, 2020 - hindawi.com
Diabetic nephropathy (DN) is a leading cause of kidney morbidity. Despite the multilayered
complexity of the mechanisms involved in the pathogenesis of DN, the conventional …

[HTML][HTML] Metabolic and epigenetic action mechanisms of antidiabetic medicinal plants

S Shanak, B Saad, H Zaid - Evidence-Based Complementary and …, 2019 - hindawi.com
Diabetes is a predominant metabolic disease nowadays due to the off-beam lifestyle of diet
and reduced physical activity. Complications of the illness include the gene-environment …

Bioactive alkaloidal and phenolic phytochemicals as promising epidrugs for diabetes mellitus 2: A review of recent development

YO Ayipo, CF Chong, HT Abdulameed, MN Mordi - Fitoterapia, 2024 - Elsevier
Abstract Type 2 diabetes (T2D) remains a major chronic metabolic disorder affecting
hundreds of millions of the global population, mostly among adults, engendering high rates …

[HTML][HTML] Insights into the uses of traditional plants for diabetes nephropathy: A review

H Shahin DH, R Sultana, J Farooq, T Taj… - Current Issues in …, 2022 - mdpi.com
Diabetic nephropathy (DN) is a serious kidney illness characterized by proteinuria,
glomerular enlargement, reduced glomerular filtration, and renal fibrosis. DN is the most …