Herein, a nano-micelle drug delivery system was developed to orally improved zingerone's
bioavailability and its antitumor effect. Indeed, zingerone-loaded d-α-tocopheryl …

This study sought to prepare a self-microemulsion drug delivery system containing
zingerone (Z-SMEDDS) to improve the low oral bioavailability of zingerone and anti-tumor …

Abstract Treatment of cancerous cells like diseases underwent huge latest advancement
scenario treatments with a molecular focus targeted therapy. However, non-specifically …

Polymeric micelles receive considerable attention as drug delivery vehicles, depending on
the versatility in drug solubilization and targeting therapy. However, their use invariably …

Itraconazole (ITZ) is a renowned antifungal medication, however its therapeutic efficacy is
limited by low solubility and oral bioavailability. The current research work attempted to …

Background As an active ingredient of Chinese herbal medicine, quercetin (QU) can
significantly induce apoptosis of tumor cells and give play to other effect such as decreasing …

Colorectal cancer, a type of malignant neoplasm originating from the epithelial cells lining
the colon and/or rectum, has been the third most frequent malignancy and one of the leading …

Background: Metformin (MET) is a well-known anti-diabetic drug that also has anti-cancer
effects. However, high therapeutic doses of MET on cancer cells and the low efficacy of …

The aim of this work is to apply Solutol® HS15 and TPGS to prepare self-assembled
micelles loading with ginsenoside Rh2 to increase the solubility of ginsenoside Rh2, hence …

Chronic Inflammatory bowel diseases are usually accompanied by opportunistic colonic
fungal infections. Itraconazole (ITZ), is a highly lipophilic broad-spectrum antifungal drug that …