The brain is the most complex organ in the body, and much of this is due to the highly
orchestrated wiring of its neurons. This thesis showcases three computational modeling …

Approximately half of the human brain consists of myelinated axons. Central nervous system
(CNS) myelin is made by oligodendrocytes and is essential for nervous system formation …

Traditionally, myelin has been portrayed as merely playing structural and supportive roles in
the nervous system, providing the ''insulation''that allows saltatory conduction of the action …

Myelination: Both Mindful and Mindless? Page 1 roles in both the emergence and extinction of
ichthyosaurs. Whether global warming is harmful or beneficial to a lineage of organism seems …

Highlights•The leading edge of myelin membrane winds around the axon while spreading
laterally.•Actin filament disassembly promotes axon wrapping by myelin …

Glial-neuron interactions and the regulation of myelin formation Page 1 Glial-neuron interactions
and the regulation of myelin formation Joseph P Doyle and David R Colman Mount Sinai …

Central nervous system myelin is a multilayered membrane produced by oligodendrocytes
to increase neural processing speed and efficiency, but the molecular mechanisms …

The evolution of complex nervous systems in vertebrates has been accompanied by, and
probably dependent on, the acquisition of the myelin sheath. Although there has been …

Myelination organizes axons into distinct domains that allow nerve impulses to propagate in
a saltatory manner. The edges of the myelin sheath are sealed at the paranodes by axon …

The myelination of axons in the central nervous system (CNS) is essential for nervous
system formation, function and health. CNS myelination continues well into adulthood, but …