Infertility is a major health problem today, affecting about 15.0% of couples trying to have a
child. Impaired fertility of the male is causative in 20.0% of infertile couples and contributory …

Male infertility affects a large proportion of the population. In spite of the magnitude of the
problem and the considerable research effort that has been made to understand its causes …

Purpose This review provides an update on the genetics of male infertility with emphasis on
the current state of research, the genetic disorders that can lead to non-syndromic male …

While 7% of the men are infertile, currently, a genetic etiology is identified in less than 25%
of those men, and 30% of the infertile men lack a definitive diagnosis, falling in the …

Background Despite the evidence of declining sperm counts worldwide and the increasing
prevalence of male infertility, there has been limited documentation of the potential causes …

The World Health Organization declaimed that infertility is a major global public health issue
of the last few decades. Infertility is commonly defined as the failure to conceive after 1 year …

OBJECTIVE: To examine whether polymorphisms within the ESR1, FSHR, ESR2, CYP19A1,
and NRIP1 genes are susceptibility factors for human male idiopathic infertility and to test …

Male infertility is a multifactorial complex disease with highly heterogeneous phenotypic
representation and in at least 15% of cases, this condition is related to known genetic …

Purpose Male infertility remains poorly understood at the molecular level. We aimed in this
study to investigate the yield of a “genomics first” approach to male infertility. Methods …

Purpose Ongoing evidence has suggested the role of male factor infertility as a potential
predictor of mortality and general health status. The aim of the present review is to update …