The development of oocytes and early embryos is dependent on mitochondrial ATP
production. This reliance on mitochondrial activity, together with the exclusively maternal …

Optimal energy production is required for oocyte and embryo development, and
mitochondrial abnormalities have devastating reproductive consequences. Improvement of …

The oocyte is recognised as the largest cell in mammalian species and other multicellular
organisms. Mitochondria represent a high proportion of the cytoplasm in oocytes and …

Oocyte quality is one of the most important factors involving in female reproduction. The
number of compromised oocytes will increase with maternal age, while mitochondrial …

Oocyte mitochondria are increased in number, smaller, and rounder in appearance than
mitochondria in somatic cells. Moreover, mitochondrial numbers and activity are narrowly …

As the vital organelles for cell energy metabolism, mitochondria are essential for oocyte
maturation, fertilization, and embryo development. Abnormalities in quantity, quality, and …

The mitochondria, present in almost all eukaryotic cells, produce energy but also contribute
to many other essential cellular functions. One of the unique characteristics of the …

With the nucleus as an exception, mitochondria are the only animal cell organelles
containing their own genetic information, called mitochondrial DNA (mtDNA). During oocyte …

The oocyte requires a vast supply of energy after fertilization to support critical events such
as spindle formation, chromatid separation, and cell division. Until blastocyst implantation …

Mitochondria are the key regulators of multiple vital cellular processes, including apoptosis,
calcium homeostasis, and the generation of ATP via the metabolic pathway known as …