The role of mitochondria as a nexus of developmental regulation in mammalian oogenesis
and early embryogenesis is emerging from basic research in model species and from …

Purpose The number of women attempting to conceive between the ages of 36 and 44 has
increased significantly in the last decade. While it is well established that women's …

Oocyte mitochondria are unique organelles that establish a founder population in primordial
germ cells (PGCs). As the oocyte matures in the postnatal mammalian ovary during …

Mitochondria have been implicated as key factors regulating female reproductive processes.
Notable progress has been made in determining the role of mitochondria with respect to …

Mitochondria play vital roles in oocyte functions and they are critical indicators of oocyte
quality which is important for fertilization and development into viable offspring. Quality …

In addition to their role in generating energy (ATP), other possible regulatory functions for
mitochondria in the mature oocyte, preimplantation stage embryo and differentiating …

Mitochondrial production of cellular energy is essential to oocyte function, zygote
development and successful continuation of pregnancy. This review focuses on several key …

The oocyte is the largest cell found in multicellular organisms. Mitochondria, as the energy
factories for cells, are found in high numbers in oocytes, as they provide the energy for …

Mitochondria have long been known to be the powerhouses of the cell but they also
contribute to redox and Ca 2+ homeostasis, provide intermediary metabolites and store …

Obesity is associated with ovulatory disorders, decreased rates of conception, infertility,
early pregnancy loss and congenital abnormalities. Poor oocyte quality and reduced IVF …