STUDY QUESTION What part do mitochondria play in cases of diminished ovarian reserve
(DOR)? SUMMARY ANSWER Mitochondrial biogenesis in cumulus cells may be linked with …

STUDY QUESTION Does in vivo aging of mouse oocytes affect mitochondrial function?
SUMMARY ANSWER Mitochondrial function was impaired in post-ovulatory in vivo-aged …

Overweight or obese women seeking pregnancy is becoming increasingly common. Human
maternal obesity gives rise to detrimental effects during reproduction. Emerging evidence …

This review examines the place of mitochondria in the life cycle through oogenesis,
ovulation and early embryogenesis. Mitochondria are semi-autonomous organelles …

Mitochondria is a powerhouse organelle involved in ATP synthesis, calcium signaling,
reactive oxygen species (ROS) by oxidative stress production, cell cycle arrest via apoptosis …

The developmental competence of mouse and human early embryos appears to be directly
related to the metabolic capacity of a finite complement of maternally inherited mitochondria …

The magnitude of the potential difference (polarity) across the inner mitochondrial
membrane (ΔΨm) determines levels of several mitochondrial activities, including ATP …

Germinal vesicle transplantation (GVT) has been proposed as a possible treatment to
correct age-related oocyte aneuploidy caused by dysfunctional ooplasm. How healthy …

Oocytes from aging ovaries contain mitochondria with morphological and genetic flaws. How
these flaws relate to phenotypes of oocyte developmental compromise associated with …

Older women are often the most challenging group of patients in fertility clinics due to a
decline in both number and overall quality of oocytes. The quality of oocytes has been linked …