[HTML][HTML] An overview of molecular mechanism, clinicopathological factors, and treatment in NUT carcinoma

QW Huang, LJ He, S Zheng, T Liu… - BioMed Research …, 2019 - hindawi.com
NUT carcinoma (NC) is a rare and poorly differentiated tumor, with highly aggressive and
fatal neoplasm. NC is characterized by chromosomal rearrangement involving NUTM1 …

[HTML][HTML] Advances in the pathogenesis and treatment of nut carcinoma: a narrative review

S Wang, J Li, W Tong, H Li, Q Feng… - Translational Cancer …, 2020 - ncbi.nlm.nih.gov
NUT carcinoma (NC) is a rare, highly invasive and fatal tumor and often misdiagnosed. It
typically arises from the mediastinum and midline organs and has complicated …

[HTML][HTML] NUT carcinoma—an underdiagnosed malignancy

UM Lauer, M Hinterleitner, M Horger… - Frontiers in …, 2022 - frontiersin.org
NUT carcinoma (NC) is a rare and highly aggressive malignancy with a dismal prognosis
and a median survival of 6–9 months only. Although very few cases of NC are reported each …

[HTML][HTML] NUT carcinoma: clinicopathologic features, molecular genetics and epigenetics

V Moreno, K Saluja, S Pina-Oviedo - Frontiers in Oncology, 2022 - frontiersin.org
Nuclear protein in testis (NUT) carcinoma is a rare, highly aggressive, poorly differentiated
carcinoma occurring mostly in adolescents and young adults. This tumor usually arises from …

Diagnosis of NUT carcinoma despite false-negative next-generation sequencing results: a case report and literature review

X Wang, J Wang, X Luo, J Lu, L Wang, Q Li… - OncoTargets and …, 2021 - Taylor & Francis
Nuclear protein in testis (NUT) carcinoma (NC) is a poorly differentiated malignant tumor
with a poor prognosis, which is caused by the NUTM1 gene rearrangement. Positive …

A case of metastatic NUT carcinoma with prolonged response on gemcitabine and nab‐paclitaxel

SA Patel, B Singer, C Shen, AM Zanation… - Clinical Case …, 2021 - Wiley Online Library
Background NUT carcinoma is an aggressive malignancy characterized by translocations in
the NUTM1 gene. There are currently no consensus treatment recommendations for NUT …

NUT carcinoma in children and adults: A multicenter retrospective study

L Lemelle, G Pierron, P Fréneaux… - Pediatric blood & …, 2017 - Wiley Online Library
Background Nuclear protein of the testis (NUT) carcinoma (formerly NUT midline carcinoma)
is an aggressive tumor defined by the presence of NUT rearrangement with a poor …

NUT Carcinoma: Clinicopathologic features, pathogenesis, and treatment

CA French - Pathology international, 2018 - Wiley Online Library
NUT carcinoma (NC) is a rare, aggressive subtype of squamous cell carcinoma defined by
rearrangement of the NUTM1 (aka NUT) gene. NC is driven by NUT‐fusion oncoproteins …

NUT carcinoma

CA French - Rare Tumors in Children and Adolescents, 2022 - Springer
NUT carcinoma (NC) is defined molecularly by rearrangement of the NUTM1 gene and is
most commonly driven by the BRD4-NUT oncoprotein. Patients are typically in their teens or …

Report of the first international symposium on NUT carcinoma

CA French, ML Cheng, GJ Hanna, SG DuBois… - Clinical Cancer …, 2022 - AACR
NUT carcinoma is a rare, aggressive cancer defined by rearrangements of the NUTM1 gene.
No routinely effective treatments of NUT carcinoma exist, despite harboring a targetable …