Brain oxygen optimization in severe traumatic brain injury phase-II: a phase II randomized trial
DO Okonkwo, LA Shutter, C Moore… - Critical care …, 2017 - journals.lww.com
Objectives: A relationship between reduced brain tissue oxygenation and poor outcome
following severe traumatic brain injury has been reported in observational studies. We …
following severe traumatic brain injury has been reported in observational studies. We …
Brain oxygenation and energy metabolism: part I—biological function and pathophysiology
A Zauner, WP Daugherty, MR Bullock, DS Warner - Neurosurgery, 2002 - journals.lww.com
Abstract CONTINUOUS OXYGEN DELIVERY and CO 2 clearance are paramount in the
maintenance of normal brain function and tissue integrity. Under normal conditions, aerobic …
maintenance of normal brain function and tissue integrity. Under normal conditions, aerobic …
The Neuroprotection Effect of Oxygen Therapy: A Systematic Review and Meta‑analysis
Z Deng, W Chen, J Jin, J Zhao - Nigerian Journal of Clinical Practice, 2018 - ajol.info
This study reviews the oxygen therapy (normobaric oxygen [NBO] and hyperbaric oxygen
[HBO]) in both stroke and traumatic brain injury (TBI) patients and meta‑analyzes the efficacy …
[HBO]) in both stroke and traumatic brain injury (TBI) patients and meta‑analyzes the efficacy …
[HTML][HTML] Monitoring cerebral oxygenation in acute brain-injured patients
C Robba, FS Taccone, G Citerio - Intensive care medicine, 2022 - Springer
Monitoring cerebral oxygenation may improve the understanding of brain dysfunction after
an acute brain injury (ABI)[1]. Indeed, ABI leads to a cascade of events resulting in altered …
an acute brain injury (ABI)[1]. Indeed, ABI leads to a cascade of events resulting in altered …
Titrating the dose of oxygen after severe traumatic brain injury in the era of precision medicine
PM Kochanek, H Bayır - Journal of Neurotrauma, 2017 - liebertpub.com
Over the past 40 to 50 years, we have made strides in understanding the molecular
underpinnings of oxidative stress and its consequences in severe traumatic brain injury …
underpinnings of oxidative stress and its consequences in severe traumatic brain injury …
[HTML][HTML] Advanced cerebral monitoring in neurocritical care
N Barazangi, JC Hemphill - Neurology India, 2008 - journals.lww.com
New cerebral monitoring techniques allow direct measurement of brain oxygenation and
metabolism. Investigation using these new tools has provided additional insight into the …
metabolism. Investigation using these new tools has provided additional insight into the …
Heterogeneity of Brain Oxidative Metabolism and Hypoxia Response: Mammalian Systems and Nature's Solutions
JF Dunn, ES Rhodes, T Panz - Oxygen Transport to Tissue XIX, 1997 - Springer
Brain ischemia (defined here as restricted flow) and/or hypoxia (defined here as a reduced
oxygen supply) caused by stroke is a major cause of death and debilitation. In addition …
oxygen supply) caused by stroke is a major cause of death and debilitation. In addition …
In Silico Model of Critical Cerebral Oxygenation after Traumatic Brain Injury: Implications for Rescuing Hypoxic Tissue
Cerebral oxygen delivery is central to the modern intensive care of patients with severe
traumatic brain injury. Low brain tissue oxygen tension (PbtO2) results from microvascular …
traumatic brain injury. Low brain tissue oxygen tension (PbtO2) results from microvascular …
Brain oxygen tension in severe head injury
WA Van den Brink, H van Santbrink… - …, 2000 - journals.lww.com
OBJECTIVE: Ensuring adequate cerebral oxygenation and perfusion is of fundamental
importance in the treatment of patients with acute cerebral disorders. Online continuous …
importance in the treatment of patients with acute cerebral disorders. Online continuous …
Association between early hyperoxia and worse outcomes after traumatic brain injury
M Brenner, D Stein, P Hu, J Kufera, M Wooford… - Archives of …, 2012 - jamanetwork.com
Objective To investigate the relationship between oxygenation and short-term outcomes in
patients with traumatic brain injury (TBI). Design Logistic regression analysis was used to …
patients with traumatic brain injury (TBI). Design Logistic regression analysis was used to …