ALIFE2 study: low-molecular-weight heparin for women with recurrent miscarriage and inherited thrombophilia-study protocol for a randomized controlled trial

PG de Jong, S Quenby, KWM Bloemenkamp… - Trials, 2015 - Springer
Background A large number of studies have shown an association between inherited
thrombophilia and recurrent miscarriage. It has been hypothesized that anticoagulant …

Antithrombotic treatment for recurrent pregnancy loss?

IA Greer - Journal of Thrombosis and Haemostasis, 2011 - Wiley Online Library
Background: Recurrent pregnancy loss (RPL) is a major issue for women's health. Acquired
and heritable thrombophilias are associated with RPL, this association could reflect a …

Thrombophilia and pregnancy complications: cause or association?

S Middeldorp - Journal of Thrombosis and Haemostasis, 2007 - Wiley Online Library
Both acquired and inherited thrombophilia is associated with an increased risk of pregnancy
failure (ie sporadic and recurrent miscarriage, late fetal loss), as well as hypertensive …

Thrombophilia investigation in Malaysian women with recurrent pregnancy loss

T Ayadurai, S Muniandy… - Journal of Obstetrics and …, 2009 - Wiley Online Library
Aim: The status of thrombophilia in Asian women with recurrent pregnancy loss (RPL) is
obscure and poorly understood. Numerous studies suggest the non‐existence or extreme …

Genetic prothrombotic risk factors in women with unexplained pregnancy loss

G Sottilotta, V Oriana, C Latella, F Luise, A Piromalli… - Thrombosis research, 2006 - Elsevier
INTRODUCTION: Inherited thrombophilia has been associated with unexplained recurrent
pregnancy loss (RPL) and stillbirth. This thrombotic tendency can manifest as thrombotic …

Multiple thrombophilic gene mutations rather than specific gene mutations are risk factors for recurrent miscarriage

CB Coulam, RS Jeyendran, LA Fishel… - American Journal of …, 2006 - Wiley Online Library
Problem Recurrent miscarriage is a heterogeneous condition. While the role of acquired
thrombophilia has been accepted as an etiology of recurrent miscarriage, the contribution of …

Maternal factor V Leiden and prothrombin mutations do not seem to contribute to the occurrence of two or more than two consecutive miscarriages in Caucasian …

K Baumann, P Beuter‐Winkler… - American Journal of …, 2013 - Wiley Online Library
Background We analysed the prevalence of the most common hereditary thrombophilia
(hTP)–factor V Leiden (FVL) mutation, prothrombin 20210 G> A substitution (PT)–and the …

Thrombophilic gene mutations and recurrent spontaneous abortion: prothrombin mutation increases the risk in the first trimester

R Pihusch, E Hiller, T Buchholz… - American Journal of …, 2001 - Wiley Online Library
PROBLEM: Thrombophilic predisposition may be one of the underlying causes of recurrent
spontaneous abortions (RSA). We studied the prevalence of five thrombophilic gene …

How strong is the association between maternal thrombophilia and adverse pregnancy outcome?: A systematic review

Z Alfirevic, D Roberts, V Martlew - … Journal of Obstetrics & Gynecology and …, 2002 - Elsevier
Objective: To determine whether inherited and acquired thrombophilias are associated with
adverse obstetric complications. Study Design: A systematic review; studies where women …

[HTML][HTML] Hereditary thrombophilias are not associated with a decreased live birth rate in women with recurrent miscarriage

H Carp, M Dolitzky, I Tur-Kaspa, A Inbal - Fertility and sterility, 2002 - Elsevier
Objective: To assesses the live birth rate without treatment in women with hereditary
thrombophilia who have recurrent miscarriage and women without thrombophilia who have …