Changes in vascular risk factors from midlife to late life and white matter lesions: a 20-year follow-up study
M Vuorinen, A Solomon, S Rovio, L Nieminen… - Dementia and geriatric …, 2011 - karger.com
Abstract Background/Aims: This study investigated the relation of midlife blood pressure,
total cholesterol, body mass index (BMI), their changes over time, apolipoprotein E, and …
total cholesterol, body mass index (BMI), their changes over time, apolipoprotein E, and …
Midlife and late‐life vascular risk factors and white matter microstructural integrity: the atherosclerosis risk in communities neurocognitive study
Background Diffusion tensor imaging measures of white matter (WM) microstructural
integrity appear to provide earlier indication of WM injury than WM hyperintensities; …
integrity appear to provide earlier indication of WM injury than WM hyperintensities; …
Aortic atherosclerosis at middle age predicts cerebral white matter lesions in the elderly
FE de Leeuw, J Cees de Groot, M Oudkerk… - Stroke, 2000 - Am Heart Assoc
Background and Purpose—MRI scans of the brains of elderly people frequently show white
matter lesions. Clinically, these lesions are associated with cognitive impairment and …
matter lesions. Clinically, these lesions are associated with cognitive impairment and …
Antihypertensive treatment and change in blood pressure are associated with the progression of white matter lesion volumes: the Three-City (3C)–Dijon Magnetic …
Background—Blood pressure (BP) is recognized as a major risk factor for white matter
lesions (WMLs), but longitudinal data are scarce, and there is insufficient evidence for the …
lesions (WMLs), but longitudinal data are scarce, and there is insufficient evidence for the …
Cardiovascular risk factors and small vessel disease of the brain: blood pressure, white matter lesions, and functional decline in older persons
HMA Abraham, L Wolfson, N Moscufo… - Journal of Cerebral …, 2016 - journals.sagepub.com
Several potential vascular risk factors exist for the development and accumulation of
subcortical white matter disease in older people. We have reported that in older people …
subcortical white matter disease in older people. We have reported that in older people …
Body mass index and white matter lesions in elderly women. An 18-year longitudinal study
DR Gustafson, B Steen, I Skoog - International Psychogeriatrics, 2004 - cambridge.org
Background: We investigated the longitudinal relationship between body mass index (BMI),
a major vascular risk factor, and white matter lesions (WMLs) in older women. Methods …
a major vascular risk factor, and white matter lesions (WMLs) in older women. Methods …
Vascular risk factors: imaging and neuropathologic correlates
DS Knopman, R Roberts - Journal of Alzheimer's disease, 2010 - content.iospress.com
Cerebrovascular disease plays an important role in cognitive disorders in the elderly.
Cerebrovascular disease and Alzheimer's disease interact on several levels, with one …
Cerebrovascular disease and Alzheimer's disease interact on several levels, with one …
Midlife vascular risk factors and their association with dementia deaths: results from a Norwegian prospective study followed up for 35 years
BH Strand, EM Langballe, V Hjellvik, M Handal… - Journal of the …, 2013 - Elsevier
There is growing evidence that midlife risk factors for vascular disease also are risk factors
for dementia, but there is still need for long-term observational studies to address this. Our …
for dementia, but there is still need for long-term observational studies to address this. Our …
High blood pressure and cerebral white matter lesion progression in the general population
BFJ Verhaaren, MW Vernooij, R de Boer, A Hofman… - …, 2013 - Am Heart Assoc
High blood pressure is considered an important risk factor for cerebral white matter lesions
(WMLs) in the aging population. In a longitudinal population-based study of 665 …
(WMLs) in the aging population. In a longitudinal population-based study of 665 …
Hyperinsulinemia and elevated systolic blood pressure independently predict white matter hyperintensities with associated cognitive decrement in the middle-aged …
Cerebrovascular disease is an independent risk factor for dementia that may also be
synergistic with Alzheimer's disease. In recent years attention has switched from cerebral …
synergistic with Alzheimer's disease. In recent years attention has switched from cerebral …